Results 51 to 60 of about 5,248,151 (199)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A Braille Trail for all: Inclusive design in the Karoo Desert National Botanical Garden

open access: yesAfrican Journal of Disability
Background: Disability-inclusive public green spaces are vital for universal accessibility and for enhancing accessible tourism. Integrating multisensory stimuli with information and communication technologies fosters inclusive, sustainable, interactive,
Susanna F. Greyling   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The great tabu : a half century of population and family planning communication [PDF]

open access: yes, 1977
"This project was supported by the Office of Population, U.S. Agency for International Development, AID/csd-1059."For more about the East-West Center, see http://www.eastwestcenter.org/The author discusses the tabus on contraceptive and sex-related ...
Stycos, J. Mayone   +1 more
core   +1 more source

Hi ChatGPT, Translate This Text into Easy Language: Is the New Easy Language Translator a Machine?

open access: yesVAKKI Publications
We are surrounded by dysfunctional texts that are burdened with various communication barriers: They are not where we are looking for them, they are written in fonts that are too small, they are completely incomprehensible or unacceptable.
Christiane Maaß
doaj   +1 more source

The Image as a Communication Tool for Virtual Museums. Narration and the Enjoyment of Cultural Heritage

open access: yesProceedings, 2017
The challenge of contemporary museums is to make content accessible to a wider audience; in this way information related to the good becomes more communicative and usable in order to enhance its uniqueness.
Andrea Casale   +2 more
doaj   +1 more source

Making online learning accessible to disabled students: an institutional case study [PDF]

open access: yes, 2006
Based on the authors’ reflections on experience working at the Open University, approaches to making online learning accessible to disabled students are considered. The considerations are applicable to all concerned with online learning and indeed anyone
Martyn Copper, Cooper, Martyn
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Population and development : requirements for rural communication strategy [PDF]

open access: yes, 1977
"This project was supported by the Office of Population, U.S. Agency for International Development, AID/csd-1059."For more about the East-West Center, see http://www.eastwestcenter.org/This paper investigates the potential for increasing the ...
Barghouti, Shawki M.   +1 more
core   +1 more source

Managing the shortage: A quantitative-qualitative study on the scale and effects of the severe lack in sign language interpreting resource in the German market

open access: yesVAKKI Publications
This study provides an insight into the extent of the shortage of sign language interpreters in Germany and the impact this has on the co-operation and workflows between hearing sign language interpreters and their deaf clients.
Laura Marie Maaß
doaj   +1 more source

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