Results 171 to 180 of about 1,355,131 (295)

Income Situation of Agricultural Households in Slovenia after EU Accession: Impacts of Different Direct Payments Policy Options [PDF]

Paper investigates income effects of different direct payments policy options after the accession of Slovenia to the EU by application of a static deterministic total income model for rural households in Slovenia (TIM).
Erjavec, Emil, Kavcic, Stane, Kozar, Maja   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Trade Shocks and Industrial Location: the Impact of EEC Accession on the UK [PDF]

This paper combines detailed production data (from the ARD) with international trade data by port to examine the impact of accession to the EEC on the location of UK manufacturing. The paper has two main objectives.
Henry Overman, L. Alan Winters
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Catching Up: The Role of Demand, Supply and Regulated Price Effects on the Real Exchange Rates of Four Accession Countries [PDF]

The main aim of this paper is to examine the exchange rate behavior of a group of four transitional, EU accession countries, with a view to making policy recommendations regarding their accession to full European Monetary Union.
Cezary Wójcik, Ronald MacDonald
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Correction: High-content screening (HCS) workflows for FAIR image data management with OMERO. [PDF]

Sci Rep
Massei R, Busch W, Serrano-Solano B, Bernt M, Scholz S, Nicolay EK, Bohring H, Bumberger J.   +7 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Emergence of Tigecycline-Resistant Pseudomonas aeruginosa Harbouring tmexC6D6-toprJ1b From Hospital Sewage in Japan. [PDF]

Environ Microbiol Rep
Maehana S, Suzuki M, Ishimura N, Izawa H, Eda R, Nakamura M, Amarasiri M, Furukawa T, Kojima F, Sei K, Kubo M.   +10 more
europepmc   +1 more source

Would a Second Transition Stage Prolong the Initial Period of Post-socialist Economic Transformation into Market Capitalism? [PDF]

The article attempts to define the relevant yardsticks that can be used to delineate the end of the transition process or, alternatively, a second stage in the post-socialist economic transformation into market capitalism.
Wladimir Andreff
core