Results 121 to 130 of about 444,502 (344)
Accessory Auricles - Report of Two Cases
, 2017 Accessory auricle is a rare anomaly with an estimated incidence rate of 0.2-0.5%. The most common form of this malformation is the accessory tragus. It may be a sign of other syndromes, such as oculo-auriculo-vertebral dysplasia (Goldenhar’s syndrome ...
Marko B. Spasić +3 more
core +2 more sources
An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors*
Journal of Biological Chemistry, 2015 Background: In (α4β2)2α4 nicotinic acetylcholine receptors, there is an agonist binding site at the α4/α4 subunit interface. Results: α2, α3, and α6 accessory subunits can form an agonist site with α4.
Jing-Yi Wang +6 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Majalah Kardiologi Indonesia, 2013 Two cases of accessory pathway that were considered uncommon are presented. The first case shows of ECG limitation to identified manifest accessory pathway location based on delta wave morphology.
doaj +1 more source
Accessory Chromosomes of Man [PDF]
Science, 1914 Since the publication of my papers on the spermatogenesis of the guinea and of the chicken respectively (Guyer †? 09a, †? 09b) in which was recorded the finding of a chromosome or chromosome complex comparable to the “? odd,― “? accessory― or “?
openaire +3 more sources
, 2016 In January, 2016, the District of Columbia Zoning Commission adopted a new zoning code. In addition to simplifying the code and adapting it to DC’s current context, the Zoning Regulations of 2016 include significant policy reforms.
Brophy, Maura
core
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Endoscopic Fusion of the Accessory Navicular Synchondrosis That Has No Diastasis
Arthroscopy Techniques, 2017 Accessory navicular bone is a common accessory ossicle of the foot and is present in 10% to 14% of normal feet. Less than 1% of the accessory navicular bones are symptomatic.
Tun Hing Lui, M.B.B.S.(HK), F.R.C.S.(Edin), F.H.K.A.M., F.H.K.C.O.S.
doaj +1 more source
Phenotypic characteristics of familial glucocorticoid deficiency (FGD) type 1 and 2 [PDF]
, 2010 Context: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder as a result of mutation in genes encoding either the ACTH receptor [melanocortin 2 receptor (MC2R)] or its accessory protein [melanocortin 2 receptor accessory ...
Metherell, LA +5 more
core +1 more source