Results 161 to 170 of about 1,274,900 (310)
Invasive Ductal Carcinoma Arising from Axillary Accessory Breast
Tae Wan Kim+7 more
openalex +1 more source
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin+9 more
wiley +1 more source
Accessory Breasts: When to Excise?
Hanan M. Alghamdi, Maha S A Abdelhadi
openaire +2 more sources
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang+6 more
wiley +1 more source
A CASE OF ACCESSORY BREAST CANCER ASSOCIATED WITH CONTRALATERAL INVASIVE DUCTAL BREAST CARCINOMA
Katsuhisa Enomoto+3 more
openalex +2 more sources
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan+13 more
wiley +1 more source
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu+17 more
wiley +1 more source
Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen+7 more
wiley +1 more source
A Case of Left Axillary Accessory Breast Cancer
Shinsuke Kanekiyo+6 more
openalex +2 more sources