Results 171 to 180 of about 1,274,900 (310)

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

open access: yesAdvanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan   +16 more
wiley   +1 more source

Fibroadenoma in axillary accessory breast mimicking carcinoma of unknown primary; a case report with literature review. [PDF]

open access: yesAnn Med Surg (Lond), 2022
Pshtiwan LRA   +6 more
europepmc   +1 more source

Controlling Release Kinetics of an Adjuvant from a Depot Improves the Efficacy of Local Immunotherapy in Metastatic Cancer

open access: yesAdvanced Science, EarlyView.
We show that intratumoral release of an immunotherapy—CpG —can be tuned with molecular precision by complexing it to an elastin‐like polypeptide (ELP). Injecting ELP‐CpG and an excipient ELP into tumors drives thermally‐triggered phase separation into a micro‐scale “sponge” depot that releases CpG at rates depending on the ELP composition, which ...
Joshua J. Milligan   +16 more
wiley   +1 more source

Accessory breast tissue

open access: hybrid, 2010
Daniel Bell, The Radswiki
openalex   +1 more source

A Rare Presentation of Accessory Breast in Axilla

open access: yesGalician Medical Journal, 2016
Isik, Arda   +4 more
openaire   +6 more sources

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su   +13 more
wiley   +1 more source

PRIMARY ACCESSORY BREAST CANCER IN A MALE-CASE REPORT AND REVIEW OF THE LITERATURE-

open access: bronze, 2011
Nobuhiro Shibata   +6 more
openalex   +2 more sources

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

open access: yesAdvanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang   +16 more
wiley   +1 more source

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