Engineering an Enzymatically Active Granular Matrix for On‐Chip Modeling of Bone‐Like Mineralization
Alkaline phosphatase (ALP)‐functionalized poly(ethylene glycol) (PEG) microgels assemble into a perfusable granular matrix for cell‐free modeling of bone‐like mineralization. Microgel‐associated enzymatic activity promotes calcium phosphate deposition, producing a calcium‐deficient, poorly crystalline apatite‐like phase, while keeping interparticle ...
Farhad Sanaei +6 more
wiley +1 more source
Preliminary Study on In Situ Immobilization of Pb, Cd, and Zn in Flotation Tailings and Metallurgical Slags Using Phosphate, Cement, and Iron-Based Additives. [PDF]
Bajda T, Korczak J.
europepmc +1 more source
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan +14 more
wiley +1 more source
Phengite-mediated fluorine and chlorine fluxes from subduction zones to the deep mantle. [PDF]
Liu Y, Wang Y, Chen C, Gao M, Xu YG.
europepmc +1 more source
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou +4 more
wiley +1 more source
Correlative optical, electron, and electrochemical microscopy assessment of localised sulphide reactivity in concrete aggregates. [PDF]
Atiba JO, Peterson K, Ogunsanya IG.
europepmc +1 more source
Advances in research on layered double hydroxides for biomedical applications
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Co-occurrence of uranium, fluoride and nitrate in Sahelian groundwater of Agadez (Niger) drives population health risks. [PDF]
Alhassane I +5 more
europepmc +1 more source
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source
The Spatial Association of Accessory Minerals with Biotite in Granitic Rocks
Clarke, B. D. +4 more
openaire +2 more sources

