Results 111 to 120 of about 2,716,201 (390)

Rethinking Strategies for a Pharmaceutical Approach to Pain Related to Connective Tissue–Related Raynaud Phenomenon in the United States

Arthritis Care &Research, EarlyView.
Objective There are no US Food and Drug Administration–approved therapies for Raynaud phenomenon (RP) in the United States. Clinical trials have been challenged by study design. Important advances in RP patient‐reported outcome measures and mechanistic quantification allow RP‐related pain characterization.
Tracy M. Frech, Charles G. Frech, W. David Merryman, Andrew Sternlicht, Justin Baba   +4 more
wiley   +1 more source

Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher, Rosario Meouchi, Anushka Irani   +2 more
wiley   +1 more source

Influence of Atrioventricular Nodal Reentrant Tachycardia Ablation on Right to Left Inter-atrial Conduction [PDF]

, 2005
Background: Radiofrequency (RF) catheter ablation is the procedure of choice for the potential cure of atrioventricular nodal reentrant tachycardia (AVNRT) with high success rates.
Akyol, Ahmet, Eksik, Abdurrahman, Erdinler, Izzet, Norgaz, Tugrul   +3 more
core   +2 more sources

Chicken Toll-like Receptor 3 Recognizes Its Cognate Ligand When Ectopically Expressed in Human Cells [PDF]

, 2007
Recognition of pathogens by toll-like receptors (TLRs) causes activation of signaling cascades that trigger cytokine secretion and, ultimately, innate immunity.
Bauer, Stefan, Kaspers, Bernd, Kothlow, Sonja, Lavric, Miha, Ohnemus, Annette, Schneider, Kirsten, Schwarz, Heike, Staeheli, Peter   +7 more
core   +1 more source

Longitudinal dissociation of atrioventricular accessory pathways

Journal of the American College of Cardiology, 1991
Unusual properties of atrioventricular (AV) accessory pathways were found during electrophysiologic investigations in four patients (three men and one woman). Anterograde longitudinal dissociation of the accessory pathway was observed in two patients and retrograde longitudinal dissociation in two others.
Atié, Jacob, Brugada, Pedro, Brugada, Josep, Smeets, Joep L.R.M., Cruz, Fernando E.S., Peres, Ayrton, Duque, Mauricio, Wellens, Hein J.J.   +7 more
openaire   +2 more sources

What Is the Role of Giant Endosomal Sorting Complexes Required for Transport (ESCRT) Structures in T Cell Activation?

Advanced Biology, EarlyView.
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma, Femmy C. Stempels, Rinse de Boer, Geert van den Bogaart   +3 more
wiley   +1 more source

NanoMOF‐Based Multilevel Anti‐Counterfeiting by a Combination of Visible and Invisible Photoluminescence and Conductivity

Advanced Functional Materials, EarlyView.
This study presents novel anti‐counterfeiting tags with multilevel security features that utilize additional disguise features. They combine luminescent nanosized Ln‐MOFs with conductive polymers to multifunctional mixed‐matrix membranes and powder composites. The materials exhibit visible/NIR emission and matrix‐based conductivity even as black bodies.
Moritz Maxeiner, Ruben Maile, Murat Cuvalli, Andreas Wolf, Ayisha Komal, Robert Oestreich, Christoph Janiak, Karl Mandel, Alexander Knebel, Klaus Müller‐Buschbaum   +9 more
wiley   +1 more source

Microguards and micromessengers of the genome [PDF]

, 2016
The regulation of gene expression is of fundamental importance to maintain organismal function and integrity and requires a multifaceted and highly ordered sequence of events.
A Bobrie, A Gioti, A Leiblich, A Lukasik, A Sharma, A Weiberg, AE Hall, AH Buck, B-C Yoo, C Braicu, C Fricke, D Green, D Haig, D Kim, DJ Sharkey, DM Pegtel, DP Bartel, E Marin-Gonzalez, E Tili, G Arnqvist, GL Hager, H Liu, H Valadi, H Zhou, J Lotvall, J Skog, JA Andres, JM Perkel, JR Chevillet, JS Parent, K Ohshima, K Sun, K Wang, L Corrigan, L Vojtech, LA McGraw, LA McGraw, LK Sirot, M Ghildiyal, M Greaves, M Mittelbrunn, MK Lawniczak, ML Squadrito, NS Barteneva, O Rechavi, P Cayirlioglu, P Kumar, P Xu, PB Medawar, PS Mitchell, S Mathivanan, S Sarker, S Weilner, S Wigby, S Wigby, T Chapman, T Chapman, T Chapman, T Chapman, T Chapman, T Dalmay, T Dalmay, T Kogure, TE Swingler, VN Kim, W Filipowicz, WX Chen, X Chen, Y Lee, Y Ouyang   +69 more
core   +1 more source

Successful Ablation of Antero-septal Accessory Pathway in the Non-Coronary Cusp in a Child

Indian Pacing and Electrophysiology Journal, 2012
A 15-year-old boy with Wolff-Parkinson-White syndrome underwent an electrophysiology study for symptoms of palpitations and persistence of pre-excitation during peak exercise.
Daisuke Kobayashi, MD, Swati O. Arya, MD, Harinder R. Singh, MD, CCDS   +2 more
doaj   +1 more source

Persistence of Functional Atrioventricular Accessory Pathways in Postseptated Embryonic Avian Hearts [PDF]

, 2006
Denise P. Kolditz, M. C. E. F. Wijffels, Nico A. Blom, Arnoud van der Laarse, Roger R. Markwald, Martin J. Schalij, Adriana C. Gittenberger–de Groot   +6 more
openalex   +1 more source