Safety and Efficacy of a Modified Catheter-Mediated Ablation of Accessory Pathways.
Shih‐Ann Chen +9 more
openalex +2 more sources
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang +10 more
wiley +1 more source
Immature dendritic cells induce hyporesponsiveness to alloantigens in vitro and prolong mouse cardiac allograft survival [PDF]
Fu, F +5 more
core
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan +20 more
wiley +1 more source
A case of successful endocardial ablation for the epicardial posteroseptal accessory pathway using open-window mapping combined with the extended early-meets-late algorithm. [PDF]
Watanabe M +5 more
europepmc +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Therapeutic strategy using radiofrequency ablation for para-Hisian accessory pathway. [PDF]
Kataoka N, Imamura T.
europepmc +1 more source
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen +12 more
wiley +1 more source
INFARTO MIOCÁRDICO ANTIGUO ENMASCARANDO UBICACIÓN VERDADERA DE UNA VÍA ACCESORIA / Old myocardial infarction disguising the real location of an accessory pathway [PDF]
Raimundo Carmona Puerta +2 more
doaj

