Results 111 to 120 of about 826,714 (280)

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Localization of accessory renal artery infarction using Tc-99m DMSA scintigraphy

, 2004
The presence of accessory renal arteries has been considered a relative contraindication in the setting of a live related renal transplant program. Failure to properly anastomose the arteries can cause segmental infarction leading to increased morbidity.
Ozcan Z., Ozbek S.S., Toz H., Dirlik A., Hoscoskun C.   +4 more
core   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Clinical Aspects of Renal Artery Variations [PDF]

, 2017
Amongst large number of anatomical variations in the vascularization of the kidney, the most common variation is the occurrence of multiple renal arteries.
Richa Gupta KunalChawla Anjali Aggarwal Tulika Gupta HarjeetKaur Daisy Sahni,
core   +1 more source

High-spatial-resolution 3D balanced turbo field-echo technique for MR angiography of the renal arteries: initial experience

, 2004
PURPOSE: To compare a multislab balanced turbo field-echo magnetic resonance (MR) angiographic technique, without the use of a contrast agent, with digital subtraction angiography (DSA) for imaging of the renal arteries.
Hoogeveen, Romhild M., Oyen, Raymond, Maleux, Geert, Coenegrachts, Kenneth L., Marchal, Guy, Hamaekers, Pascal, Bosmans, Hilde, Bielen, Didier, Maes, Frederik, Vaninbroukx, Johan A.   +9 more
core   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

Phytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko, Victoriya Georgiyants, Liudas Ivanauskas, Olha Mykhailenko   +3 more
wiley   +1 more source

Quantitative analysis of renal arterial variations affecting the eligibility of catheter-based renal denervation using multi-detector computed tomography angiography

, 2020
Catheter-based renal denervation (RDN) was introduced to treat resistant hypertension. However, the reduction in blood pressure after the RDN was modest.
Won Hoon Song, Choi Eue-Keun, Jeong Chang Wook, PARK, SUNG MIN, BAIK, JIN HWAN, Kim Hyeon Hoe, Lee Hae-Young   +6 more
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Renal Ectopy and Renal Artery Anomaly in a Young Patient

Turkish Journal of Nephrology, 2019
We detected renal ectopy and renal artery anomaly in a young hypertensive patient followed in our clinics. We discussed not the importance of renal ectopy but that of the existence of multiple renal arteries in the etiology of hypertension.
Neslihan SOYSAL, Kutsi KÖSEOĞLU, H. Meltem SÖNMEZ, Can Zafer KARAMAN   +3 more
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