Results 221 to 230 of about 1,142,037 (288)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

open access: yesPediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak   +5 more
wiley   +1 more source

Clinical Features, Treatments, and Outcomes of an International Cohort of 96 Children with Takayasu Arteritis

open access: yesACR Open Rheumatology, Volume 8, Issue 11, November 2026.
Objective To characterize the clinical features, treatment, and outcomes of a large, international cohort of childhood‐onset Takayasu arteritis (cTAK). Methods Patients with a diagnosis of cTAK were identified in A Registry of Childhood Vasculitis and divided into subcohorts by era‐of diagnosis: pre‐biologic (PB; 1986–2006), early biologic (EB; 2007 ...
James Bistolarides   +29 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Catheter-Based Renal Denervation in Uncontrolled and Resistant Hypertension: Evidence, Guidelines, Special Populations and Clinical Implementation. [PDF]

open access: yesJ Cardiovasc Dev Dis
Skalidis I   +19 more
europepmc   +1 more source

Perioperative Anaphylaxis and Respiratory Failure During AVF Surgery in an End‐Stage Renal Disease Patient

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Perioperative anaphylaxis can cause sudden, catastrophic respiratory and cardiovascular collapse in high‐risk ESRD patients, even during regional anesthesia. Early recognition, prompt epinephrine administration, serum tryptase measurement, vigilant respiratory monitoring, and multidisciplinary preparedness—including ECMO capability—are ...
Madeline Dow   +2 more
wiley   +1 more source

Extensive Stray‐Dog Mauling as Major Contaminated Crush Trauma Causing Severe Rhabdomyolysis, Acute Kidney Injury, and Overt Disseminated Intravascular Coagulation: Recovery Without Renal Replacement Therapy

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT An adolescent male developed severe rhabdomyolysis, acute kidney injury, overt disseminated intravascular coagulation, and respiratory fluid overload after extensive stray‐dog mauling. The course reflected overlapping traumatic, inflammatory, and infectious mechanisms.
Rafil A. Bshara   +4 more
wiley   +1 more source

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