Results 81 to 90 of about 125,293 (313)

Understanding target-driven action in A&E performance using simulation [PDF]

, 2009
Many computer simulation models of emergency departments have been developed to aid clinicians and managers to maintain and improve the performance of their departments. A model is presented that can also be used to understand changes in performance that
Gunal, M, Pidd, M
core  

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Factors influencing passenger evacuation from smaller transport aircraft including the operation of the Type-III exit [PDF]

, 2008
Accident reports and experimental research have documented difficulties when operating and evacuating through overwing emergency exits. The factors influencing exit operation and evacuation from smaller regional transport aircraft are less understood ...
Wilson, Rebecca
core  

Supratherapeutic drug concentration triggers: A novel data‐driven approach to assess their value for medication safety surveillance in intensive care

British Journal of Clinical Pharmacology, EarlyView.
Aims Electronic triggers (e‐triggers) are used as screening signals to detect potential adverse drug events (ADEs) and offer an effective system level approach for medication safety surveillance. Their clinical utility is typically evaluated through time‐consuming manual chart review by experts, limiting implementation.
Anne Paulien Langermans, Izak A. R. Yasrebi‐de Kom, Dylan Wayne de Lange, Nicolette Fransisca de Keizer, Joanna E. Klopotowska, on behalf of the RESCUE Study group, C. S. C. Bouman, E. N. van Roon, P. F. Schutte, J. ten Cate, D. van Balen, S. Hendriks, C. Lau, W. J. Vermeijden, A. Beishuizen, J. B. Masselink, P. E. Spronk, H. J. M. van Kan, P. W. de Feiter, E. J. Wils, A. Wieringa, A. J. Valkenburg, W. M. van den Bergh, M. H. Renes, W. Bult, E. de Jonge, M. Hoeksema, E. J. Wesselink, I. M. Purmer, B. E. Bosma, S. H. W. van Bree, H. J. W. Lammers, R. J. Bosman, E. J. F. Franssen, A. Karakus, M. Sigtermans, E. M. Kuck, D. A. Dongelmans, M. J. H. Aries, E. V. Uijtendaal, M. C. Reuland   +40 more
wiley   +1 more source

A comparative study between point‐of‐care hemoglobin (capillary samples) and laboratory hemoglobin result (venous samples)

Hong Kong Journal of Emergency Medicine
Objective Point‐of‐care tests (POCTs) are commonly utilized in emergency departments. The purpose of this study was to evaluate accuracy and clinical utility of capillary POCT Hemocue (POCT Hcue) in emergency department setting.
Chun Hiu Yu, Shing Kit Tommy Lam
doaj   +1 more source

Successful extracorporeal cardiopulmonary resuscitation with percutaneous coronary intervention after nearly three hours of refractory out-of-hospital cardiac arrest: a case report

Resuscitation Plus
Background: Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a rescue strategy for refractory cardiac arrest. However, evidence supporting ECPR after extremely prolonged cardiopulmonary resuscitation (CPR) exceeding 150 min in non ...
Rongheng Lu, Aijun Shan, Shaoxi Chen
doaj   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Success and Failure in the Simulation of an Accident and Emergency Department [PDF]

, 2009
Healthcare simulation has the potential to offer many benefits but the implementation is often problematic. This paper describes the development of a simulation of an Accident and Emergency Department in an NHS hospital.
Mould, Gillian, Gillian Mould, Ghattas, Mikhail, Bowers, John, John Bowers, Mikhail Ghattas   +5 more
core   +1 more source

‘Where are the adults?’: Troubling child‐activism and children's political participation

British Educational Research Journal, EarlyView.
Abstract Children's political participation is a well‐established theme in childhood studies. In this article we offer an original account of child activism that takes into account the entangled and emergent aspect of children as activists. We begin with a historical and a conceptual review, noting the importance of mid‐20th century developments such ...
Sharon Hunter, Claire Cassidy
wiley   +1 more source

A prospective randomized crossover manikin study comparing GlideScope® video laryngoscopy and direct laryngoscopy for impacted fish bone removal in a simulated difficult airway

Hong Kong Journal of Emergency Medicine
Background Fish bone ingestion is a common emergency presentation. Direct laryngoscopy (DL) is the conventional bedside technique, but it can be limited in anatomically challenging airways.
Matthew Chi Yeung Lung, Wai Yin Leung, Chun Tat Lui   +2 more
doaj   +1 more source