Results 21 to 30 of about 2,681,800 (232)

Mesothelin Gene Variants Affect Soluble Mesothelin-Related Protein Levels in the Plasma of Asbestos-Exposed Males and Mesothelioma Patients from Germany

Biology, 2022
Malignant mesothelioma (MM) is a severe disease mostly caused by asbestos exposure. Today, one of the best available biomarkers is the soluble mesothelin-related protein (SMRP), also known as mesothelin.
Hans-Peter Rihs, Swaantje Casjens, Irina Raiko, Jens Kollmeier, Martin Lehnert, Kerstin Nöfer, Kerstin May-Taube, Nina Kaiser, Dirk Taeger, Thomas Behrens, Thomas Brüning, Georg Johnen   +11 more
doaj   +1 more source

Emergence of Informal Safety Leadership: A Social–Cognitive Process for Accident Prevention

Production and operations management, 2021
As an important domain of disaster management, accident prevention is an urgent and crucial subject because of the high frequency and severe consequences of industrial accidents in recent times.
Chunlin Wu, Han Yao, Xin Ning, Lei Wang
semanticscholar   +1 more source

Heart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults

Journal of Occupational Medicine and Toxicology, 2020
Background Exposure to airborne zinc oxide (ZnO) particles occurs in many industrial processes, especially in galvanizing and welding. Systemic inflammation after experimental inhalation of ZnO particles has been demonstrated previously, but little is ...
Assem Aweimer, Birger Jettkant, Christian Monsé, Olaf Hagemeyer, Vera van Kampen, Benjamin Kendzia, Vitali Gering, Eike-Maximilian Marek, Jürgen Bünger, Andreas Mügge, Thomas Brüning, Rolf Merget   +11 more
doaj   +1 more source

Effects of occupational health and safety management systems implementation in accident prevention at a Harare beverage company

Cogent Engineering, 2022
Occupational health and safety management (OHSMS) systems are recognised internationally as highly flexible and can be tailored to all sizes and types of businesses to manage accidents, injuries, fatalities and health risks at workplaces.
T. Musungwa, P. Kowe
semanticscholar   +1 more source

Re-evaluation of potential predictors of calretinin and mesothelin in a population-based cohort study using assays for the routine application in clinical medicine

BMJ Open, 2021
Objectives Calretinin and mesothelin are molecular markers for the detection of malignant mesothelioma at early stages. Our objective was the re-evaluation of factors influencing calretinin and mesothelin concentrations in plasma of cancer-free men in ...
Beate Pesch, Thomas Brüning, Karl-Heinz Jöckel, Daniel Weber, Swaantje Casjens, Georg Johnen, Irina Raiko, Dirk Taeger, Carmen Töpfer, Sandra Schonefeld   +9 more
doaj   +1 more source

Assessment of MYC and TERT copy number variations in lung cancer using digital PCR

BMC Research Notes, 2023
Objective Lung cancer is the second most frequent cancer type and the most common cause of cancer-related deaths worldwide. Alteration of gene copy numbers are associated with lung cancer and the determination of copy number variations (CNV) is ...
Alexander Brik, Katharina Wichert, Daniel G. Weber, Katja Szafranski, Peter Rozynek, Swetlana Meier, Yon-Dschun Ko, Reinhard Büttner, Klaus Gerwert, Thomas Behrens, Thomas Brüning, Georg Johnen   +11 more
doaj   +1 more source

Circulating long non-coding RNA GAS5 (growth arrest-specific transcript 5) as a complement marker for the detection of malignant mesothelioma using liquid biopsies

Biomarker Research, 2020
Background For the detection of malignant mesothelioma additional markers are needed besides the established panel consisting of calretinin and mesothelin. The aim of this study was the identification and verification of long non-coding RNAs (lncRNAs) as
Daniel G. Weber, Swaantje Casjens, Alexander Brik, Irina Raiko, Martin Lehnert, Dirk Taeger, Jan Gleichenhagen, Jens Kollmeier, Torsten T. Bauer, Thomas Brüning, Georg Johnen, the MoMar study group   +11 more
doaj   +1 more source

Biomonitoring of polycyclic aromatic hydrocarbons in firefighters at fire training facilities and in employees at respiratory protection and hose workshops

Frontiers in Public Health, 2023
IntroductionPolycyclic aromatic hydrocarbons (PAHs) are carcinogenic to humans and are formed by incomplete combustion. PAHs are always present during firefighting operations, and fire department members can be exposed to them in the workplace.MethodsIn ...
Stephan Koslitz, Birgit Heinrich, Heiko U. Käfferlein, Holger M. Koch, Tim Pelzl, Katrin Pitzke, Daniel Köster, Tobias Weiß, Volker Harth, Thomas Brüning, Thomas Behrens, Dirk Taeger   +11 more
doaj   +1 more source

Are circulating microRNAs suitable for the early detection of malignant mesothelioma? Results from a nested case–control study

BMC Research Notes, 2019
Objective Malignant mesothelioma is an aggressive cancer of the serous membranes. For the detection of the tumor at early stages non- or minimally-invasive biomarkers are needed.
Daniel Gilbert Weber, Alexander Brik, Swaantje Casjens, Katarzyna Burek, Martin Lehnert, Beate Pesch, Dirk Taeger, Thomas Brüning, Georg Johnen, the MoMar study group   +9 more
doaj   +1 more source

Concentration-dependent systemic response after inhalation of nano-sized zinc oxide particles in human volunteers

Particle and Fibre Toxicology, 2018
Background Inhalation of high concentrations of zinc oxide particles (ZnO) may cause metal fume fever. In an earlier human inhalation study, no effects were observed after exposure to ZnO concentrations of 0.5 mg/m3.
Christian Monsé, Olaf Hagemeyer, Monika Raulf, Birger Jettkant, Vera van Kampen, Benjamin Kendzia, Vitali Gering, Günther Kappert, Tobias Weiss, Nadin Ulrich, Eike-Maximilian Marek, Jürgen Bünger, Thomas Brüning, Rolf Merget   +13 more
doaj   +1 more source