Results 181 to 190 of about 857,434 (290)

Quality of Clinical Notes Created by Ambient Listening Generative AI: Pragmatic Prospective Pilot Study.

open access: yesJMIR Med Inform
Taylor SL   +9 more
europepmc   +1 more source

Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA. [PDF]

open access: yesEmerg Infect Dis
Nakagun S   +9 more
europepmc   +1 more source

Limited genome evolution of <i>Cryptococcus neoformans</i> following an accidental infection in the research laboratory. [PDF]

open access: yesASM Case Rep
Fan Y   +7 more
europepmc   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

open access: yesAdvanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu   +4 more
wiley   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

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