Results 181 to 190 of about 304,036 (300)

Suicide among children and adolescents in India as a public mental health priority. [PDF]

open access: yesDiscov Ment Health
Ramakrishnan T   +7 more
europepmc   +1 more source

Targeting Nupr1‐Mediated p53 Mitochondrial Sequestration Alleviates Aortic Dissection by Restoring the Gadd45b‐Dependent Survival Program

open access: yesAdvanced Science, EarlyView.
This study identifies Nupr1 as a crucial stress‐responsive orchestrator driving AD. Under severe stress, Nupr1 massively accumulates within mitochondria to sequester p53, triggering apoptosis and concurrently repressing the Gadd45b‐mediated survival program.
Xi Yang   +14 more
wiley   +1 more source

High‐Efficiency InGaP‐on‐Insulator Microresonator Nonlinear Conversion and Entanglement Generation

open access: yesAdvanced Science, EarlyView.
Sulfur treatment of InGaP‐on‐Insulator (InGaP‐OI) significantly reduces surface roughness, passivates surface states, and lowers propagation loss at visible wavelengths, enabling efficient nonlinear frequency conversion and photon‐pair generation.
Xuefeng Li   +11 more
wiley   +1 more source

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li   +11 more
wiley   +1 more source

Rapid Solidification Brings Ultralow Thermal Conductivity and Superior Thermoelectric Performance for Intrinsic GeTe Alloy

open access: yesAdvanced Science, EarlyView.
Rapid solidification with glass fluxing is first applied to the intrinsic GeTe alloy and achieves large undercooling within 2 h. This enables partial retention of the high‐temperature cubic phase at room temperature and forms a crystallographically oriented α+β dual‐phase structure and a hierarchical defect network.
Guanghui Liu   +4 more
wiley   +1 more source

Defining nonfatal opioid overdoses using administrative health data in the United States and Canada: A scoping review. [PDF]

open access: yesPrev Med Rep
Marziali ME   +7 more
europepmc   +1 more source

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