Results 211 to 220 of about 831,122 (329)

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

open access: yesAdvanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu   +7 more
wiley   +1 more source

Embedding Monodisperse LaOx Into Pt Nanoclusters for Ultra‐Stable and Efficient Hydrogen Isotope Oxidation

open access: yesAdvanced Science, EarlyView.
The introduction of isolated LaOx species into Pt nanoclusters confined within the silicalite‐1 zeolite significantly enhanced the oxidative removal of hydrogen isotopes. Under reaction conditions of 50 °C and GHSV of 72,000 mL·g−1·h−1, the catalyst achieved an excellent H2 conversion efficiency of over 99%.
Guilin Wei   +8 more
wiley   +1 more source

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

open access: yesAdvanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang   +8 more
wiley   +1 more source

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