Results 221 to 230 of about 114,968 (254)

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Adaptive Mechanisms of Endemic Fish <i>Triplophysa yarkandensis</i> in the Tarim River Basin of Northwestern China. [PDF]

Animals (Basel)
Bibi S, Zhu Y, Liu C, Yang L, Wang K, Zhu A, Yu L, Song Y, Li H, Huo B, Chen S.   +10 more
europepmc   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

Advanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim, Jiwon Lee, Minjeong Kang, Sung Sun Yim, Donghui Choe, Byung‐Kwan Cho   +5 more
wiley   +1 more source

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

Advanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu, Xinyuan Zhang, Xinyi Chen, Jiaxin Shi, Meng Xu, Fuhao Wang, Jinling Lv, Jiaman Sun, Weiyi Niu, Zihan Liu, Li Li, Fufeng Liu, Xiangming Wang   +12 more
wiley   +1 more source

Increasing risk of vapor pressure deficit exceeding critical thresholds for tree growth. [PDF]

Proc Natl Acad Sci U S A
Li T, Chen HW, Chen D, Xiao J, Guo L, Liu L, Shi F, Yuan W, Zhong Z, Zheng H, He B.   +10 more
europepmc   +1 more source

Oral Actinomyces Species Exposure is Associated with Anxiety‐Like Behavior, Mitochondrial Remodeling, and Altered GABAergic Pathways

Advanced Science, EarlyView.
Oral exposure to cannabis‐associated Actinomyces species, particularly A. meyeri, is associated with anxiety‐like behavior in mice in the absence of detectable bacterial translocation or overt systemic inflammation. These findings support a potential oral‐brain metabolic axis involving candidate metabolites such as arginine and argininosuccinate ...
Tabinda Salman, Zhenwu Luo, Douglas Johnson, Arshad A. Noorani, Zhuang Wan, Bogdan Bordieanu, Zhi‐wei Ye, Rachel D. Penrod, Hongxu Xian, Sylvia Fitting, Peter W. Kalivas, Wei Jiang   +11 more
wiley   +1 more source

Conservative versus flexible physiological and metabolic acclimation of Norway spruce and European beech under elevated CO2, nitrogen supply and water availability. [PDF]

Tree Physiol
Ofori-Amanfo KK, Klem K, Holub P, Veselá B, Oravec M, Večeřová K, Agyei T, Sándor R, Juráň S, Grace J, Marek MV, Urban O.   +11 more
europepmc   +1 more source

Phylogenomic diversity and chromatic acclimation in phycoerythrin-containing <i>Microcystis aeruginosa</i>. [PDF]

Microb Genom
Tanabe Y, Yamaguchi H, Sano T.
europepmc   +1 more source

Combined Transcriptomic and Histological Profiling Uncover Hepatic Regulatory Hierarchy of Triploid <i>Oncorhynchus mykiss</i> Under Interactive Salinity, Temperature and Body Weight Regimes. [PDF]

Biology (Basel)
Sui Y, Ji Y, Hu H, Ren Y, Qin B, Ying N, Lin T, Li S, Zheng H, Li L.   +9 more
europepmc   +1 more source