A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
Inter-individual variability in physiological adaptations during heat acclimation in adults: Contributions of body mass index and body size. [PDF]
Brazelton SC +4 more
europepmc +1 more source
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen +6 more
wiley +1 more source
The photoacclimation state of stolen chloroplasts affects the light preferences in the photosynthetic sea slug Elysia crispata. [PDF]
Vital XG +4 more
europepmc +1 more source
The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang +8 more
wiley +1 more source
Integrated response of the zebrafish (Danio rerio) cardiovascular system to hypoxia acclimation. [PDF]
Manchester EA, Gillis TE.
europepmc +1 more source
We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp +12 more
wiley +1 more source
Functional and metabolomic analyses of brown adipose tissue during cold-deacclimation reveal rapid N-acetylated amino acid adaptations. [PDF]
Pileggi CA +10 more
europepmc +1 more source
A rapid aureochrome opto-switch enables diatom acclimation to dynamic light [PDF]
Huan Zhang +12 more
openalex +1 more source

