Results 201 to 210 of about 619,868 (307)

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Ethical, legal, and social issues of AI use in emergency healthcare: a scoping review. [PDF]

BMC Med Inform Decis Mak
Lim JE, Siddiqui FJ, Ballantyne A, Dunn M, Prince S, Wilkinson D, Lewis J, Yoon S, Savulescu J, Schaefer GO.   +9 more
europepmc   +1 more source

8. Business Administration Students Perception of Environmental Accounting [PDF]

, 2017
Andreja Lutar Skerbinjek, Matjaž Denac, Lidija Hauptman   +2 more
openaire   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Robots and AI are not one moral category: why the distinction matters for ethical and conscious systems. [PDF]

Front Robot AI
Küçükuncular A.
europepmc   +1 more source

Accountability of public administration to citizens

, 2015
Renders, David, Outline of Belgian administrative law   +1 more
openaire   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Mechanisms for stimulating facility quality improvement: A positive deviance study of Tanzania's Star Rating Assessment. [PDF]

PLOS Glob Public Health
Roder-DeWan S, Gage A, Shamba D, Rajab H, Somba M, Mohamed M, Ramesh M, Yahya T, Eliakimu E.   +8 more
europepmc   +1 more source

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon, Albert A. Antolin, Alan M. Jones   +2 more
wiley   +1 more source

In the room but not on the byline: trust, fear, and the human role in addiction science in the age of AI. [PDF]

Front Sociol
Bahji A.
europepmc   +1 more source