Results 141 to 150 of about 8,026,686 (318)

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Extended exergy accounting of agricultural resources in China's four provinces of mountains and rivers. [PDF]

Sci Rep
Qi H, Dong Z, You X, Zhou S, Zhu Y.
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Clinical Value of Low-Dose Spiral CT Combined with Serum CEA in the Differential Diagnosis of Early Lung Cancer. [PDF]

Cancer Manag Res
Jin J, Wu L.
europepmc   +1 more source

IV.—Account of Experiments upon the Force of the Waves of the Atlantic and German Oceans [PDF]

Thomas R. Stevenson
openalex   +1 more source

Financial Accounting Information and Corporate Governance

, 2001
Robert Bushman, Abbie J. Smith
semanticscholar   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Marine ecosystem services and natural capital in China: Opportunities for improved understanding, valuing, and policy. [PDF]

PNAS Nexus
McCook LJ, Cai L, Yeung CW, Chen S, Ouyang Z, Ang P, Bordt M, Cao L, Chen Z, Han B, Huang H, Lei X, Lian J, Li F, Xue G, Zhao P.   +15 more
europepmc   +1 more source

XI. Account of Cædmon's Metrical Paraphrase of Scripture History, an illuminated Manuscript of the Tenth Century, preserved in the Bodleian Library at Oxford. Communicated by Henry Ellis, Esq. F.R.S., Secretary, in a Letter to the Right Hon. George Earl of Aberdeen, K.T., President [PDF]

Henry Ellis
openalex   +1 more source

Osmotic pressure‐induced calcium response states

FEBS Open Bio, EarlyView.
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao, Keiji Naruse, Masatoshi Morimatsu   +2 more
wiley   +1 more source