Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Carbon emissions accounting and uncertainty analysis in campus settings: A case study of a university in Sichuan, China. [PDF]
Yang C, Yao T, Shiming D, Jiang W.
europepmc +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao+4 more
wiley +1 more source
Corrigendum: Development of a 50K SNP array for whole-genome analysis and its application in the genetic localization of eggplant (Solanum melongena L.) fruit shape. [PDF]
Yu C+11 more
europepmc +1 more source
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
Carbon footprint analysis and emission reduction pathways of Bogie frame manufacturing process in Urban Rail Transportation. [PDF]
Zhou J, Wang R, Liu C.
europepmc +1 more source
VI. Account of a book. - The antiquities of Palmyra alias Tadmor; built by King Soloman in the desart of Arabia: Containing the history of that city and its emperors, from its foundation to this present time. By Ab. Seller. 8˚ [PDF]
Ab. Seller
openalex +1 more source
A Continuance of the Case of the Welsh Fasting Girl: With an Account of the Post Mortem Appearances [PDF]
Thomas Lewis
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Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel+4 more
wiley +1 more source