Results 71 to 80 of about 5,803,880 (315)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The procedure of evaluating the quality of accounting software

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2019
The article gives an overview of literary sources regarding the issues of software efficiency and reliability; analyzes international standards that regulate the qualitative characteristics of software products at different stages of their life cycle ...
K.О. Volska
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tax stimulation of innovative activity: an accounting dimension

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2019
In the early stages of the establishment of an innovative enterprise, tax stimulation is an effective means of saving working capital that can be used for other purposes in order to develop business.
N.I. Tsenkler
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Accounting in the management of transport logistics: organizational provisions

open access: yesПроблеми теорії та методології бухгалтерського обліку, контролю і аналізу, 2019
The article investigates the essence of the concept of «transport logistics» and substantiates that it is an optimally constructed, from an economic point of view, system of prompt address delivery of cargo.
I.M. Vygivska, K.I. Yahnych
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Forced labor in accounting during World War II. The case of the company SS Ostindustrie GmbH [PDF]

open access: yesZeszyty Teoretyczne Rachunkowości
Purpose: The aim of the paper is to examine the representation of forced labor in the accounting system and to analyze, interpret, and evaluate the accounting regulations of the company Osti (SS Ostindustrie GmbH).Methodology/approach: The historical ...
Mikołaj Turzyński, Adam Kędrzyński
doaj   +1 more source

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