Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
Pentoxifylline and Tocopherol for the Management of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Retrospective Clinical Audit. [PDF]
Antibiotics (Basel)Lombardi N +5 more
europepmc +1 more source
Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors
British Journal of Clinical Pharmacology, EarlyView.Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem +5 more
wiley +1 more source
Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
A comprehensive dataset on stakeholder participation in international accounting standards board's due process (2001-2024): Insights into legitimacy, engagement, and influence in international accounting standard-setting. [PDF]
Data BriefMolina-Sánchez H +2 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire +3 more
wiley +1 more source
‘Where are the adults?’: Troubling child‐activism and children's political participation
British Educational Research Journal, EarlyView.Abstract Children's political participation is a well‐established theme in childhood studies. In this article we offer an original account of child activism that takes into account the entangled and emergent aspect of children as activists. We begin with a historical and a conceptual review, noting the importance of mid‐20th century developments such ...
Sharon Hunter, Claire Cassidy
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Antifungal Stewardship in the Pediatric Intensive Care Unit: Time is of the Essence. [PDF]
Infect Drug ResistChorafa E +4 more
europepmc +1 more source
British Educational Research Journal, EarlyView.Abstract This paper explores the growing influence of young people's activism in UK museums and its educational implications. It draws on a five‐year collaborative programme (2019–2023) with young people of colour (16–28) in a university museum setting, focusing on a Young Collective established to address cultural inequalities.
Sadia Habib
wiley +1 more source