Results 211 to 220 of about 16,859,237 (253)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Information accountability

Communications of the ACM, 2008
With access control and encryption no longer capable of protecting privacy, laws and systems are needed that hold people accountable for the misuse of personal information, whether public or secret.
Daniel J. Weitzner   +5 more
openaire   +4 more sources

An information model for metering and accounting

2004 IEEE/IFIP Network Operations and Management Symposium (IEEE Cat. No.04CH37507), 2004
This paper proposes extensions to DMTF's CIM Metrics model and introduces a new CIM schema for representing metering and accounting information. Usage accounting is an essential component infrastructure. It is needed for purposes such as resource provisioning, capacity planning, auditing, and for charging the customers. Though some efforts are underway
Vikas Agarwal   +2 more
openaire   +1 more source

Outsourcing of Accounting Information Systems

2017
This chapter begins by defining outsourcing, clarifying the difference with offshoring and providing examples of the numerous ways outsourcing can be used for Accounting Information Systems. Outsourcing of information systems activities continues to grow. Companies regularly use a combination of employees, local vendors and offshore providers for their
Benoit A. Aubert, Jean-Grégoire Bernard
openaire   +1 more source

Accounting Information Systems: The Scope of Blockchain Accounting

2020
Distributed Ledger Technology—of which Blockchain is an example—is revolutionizing different sectors, creating new challenges and new opportunities. In this paper, we will investigate the impact of this technology on Accounting and Accounting Information Systems (AIS).
openaire   +3 more sources

The role of accounting in the informal economy

Journal of Accounting and Economics
<div> <p>Using novel survey data from 1,426 firms in Guatemala, Honduras, and El Salvador, we examine the voluntary adoption of accounting systems by microenterprises operating in the informal economy and its association with access to credit and business growth.
Marcela Aguilar, Gary Lind, K. Ramesh
openaire   +1 more source

Information Consequences of Accounting Conservatism

European Accounting Review, 2011
We study the information consequences of conservatism in accounting. Prior research shows that information asymmetries in capital markets lead to firm-level increases in conservatism. In this paper, we further argue that increases in conservatism improve the firm information environment and lead to subsequent decreases in information asymmetries ...
Juan Manuel García Lara   +2 more
openaire   +1 more source

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