ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Comparing Different Approaches of (Not) Accounting for Rapid Guessing in Plausible Values Estimation. [PDF]
Welling J, Zink E, Gnambs T.
europepmc +1 more source
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Transparency, robustness, and consistency in aboveground forest carbon quantification methodologies used for tropical forest carbon projects: a review in Southeast Asia. [PDF]
Zhou Y, Lau Y, Tan ZD, Tang H, Taylor D.
europepmc +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Accounting for missing data in public health research using a synthesis of statistical and mathematical models. [PDF]
Zivich PN +4 more
europepmc +1 more source
Accounting Information Systems and decision-making
Teittinen Henri Viljami, Granlund Markus
openaire +2 more sources
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Global health burdens of plastics: a lifecycle assessment model from 2016 to 2040.
Deeney M +6 more
europepmc +1 more source
Green accounting and ESG-driven eco-efficiency in European financial institutions: A two-stage DEA-CRITIC-TOPSIS evaluation. [PDF]
Sklavos G +3 more
europepmc +1 more source

