Results 101 to 110 of about 2,187,171 (331)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Bibliometric Panorama of Accounting Information System Research Evolution

Acta Informatica Pragensia
Accounting information systems (AIS) are closely connected with using automated accounting data processing technologies, which increase reliability and prompt information delivery to stakeholders for management decision-making. The purpose of the article
Hanna Mysaka, Ivan Derun
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

New Valences for the Financial-Accounting System [PDF]

A new approach to a company’s information systems is needed, if we take into consideration the globalization process of the economy, the intensified competition, the impose of new qualitative demands or the adjustment to new accounting standards.
Adrian LUPASC, Cristina Gabriela ZAMFIR, Ioana LUPASC   +2 more
core  

Rancangan Penyusunan Sistem Informasi Akuntansi pada Pemerintah Daerah Guna Meningkatkan Good Governance dan Tata Pelaporan yang Sesuai dengan Standar Akuntansi Sektor Publik (Studi Kasus di Pemerintah Kabupaten Sukoharjo) [PDF]

, 2015
The problem to be solved in this study is how suitability of financial management with government accounting standards, how compliance with the legislation in force, and how the implementation of accounting information systems that exist in Sukoharjo ...
Ariyanto, J. (Jonet), Sohidin, S. (Sohidin), Witurachmi, S. (Sri)   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Development of Education Accounting Information System

Jati
The purpose of this research is to develop an education accounting information system and determine the feasibility of using an education accounting information system. This research and development used the ADDIE model.
Carolina Lita Permatasari, Dwi Iga Luhsasi, Shafira Salwa Salsabila   +2 more
doaj   +1 more source

Can an Accounting Information System Substitute an Accountant?

Advanced Business and Finance, 2016
The development of modern technologies in accounting models has got a great foundation for growth. Defining accounting as a system, it is obvious that the data of such a system will be based on quite familiar to us principles - mathematics. The earliest reference to the fact that the basis of accounting is just a mathematical component contained the ...
openaire   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source