Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The aim of this study is to examine the information quality and its effect on performance of Iraqi companies. Organizations were found aware on the need to have quality of information as to cope with environmental uncertainty. Most organizations agree on
Mohammed Sami
doaj
THE QUALITY AND UTILITY OF ANNUAL FINANCIAL REPORTS BETWEEN EXPECTATIONS AND REALITY [PDF]
Any company makes its presence felt in the market by providing financial - accounting. Users will be more interested in issuing entity, to the extent that the information provided is attractive and quality, showing favorable results.
Magdalena Mihai, Adriana Craitar
doaj
Accounting Information System User Satisfaction: A Survey of Indonesian State-Owned Banks
The objective of this study is to explore accounting information system user satisfaction, particulary, this study examines the level of accounting information system user satisfaction among state-owned banks in Indonesia. User satisfaction is generally
Sambas Ade Kesuma +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
This study examines how information technology (IT) capability influences Accounting Information System (AIS) quality and Financial Reporting Quality (FRQ) in Indonesian local governments.
Ahyar Muhammad Diah +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
What Determine Accounting information System Implementation? Evidence From Indonesia
This study is about how the implementation of accounting information systems produces quality of financial information on State Owner Enterprises in Indonesia.
Sri Dewi Anggadini
doaj
The Role of Accountability as a Mediating Variable of Accounting Information System Quality on Financial and Non-Financial [PDF]
This research aims to examine and obtain empirical evidence of the influence of the quality of accounting information systems on financial and non-financial performance in village government Wonosobo Regency.
Tahar Afrizal, Oktiyani Yona
doaj +1 more source

