Results 61 to 70 of about 701,246 (206)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Value relevance of accounting information in selected Middle East countries [PDF]

open access: yes, 2010
In the past, stock markets in the Middle East have been widely ignored by international investors due to imposed limitations on foreign stock ownership, the lack of common accounting standards and corporate transparency, or they have been simply ...
Khanagha, Jamal Barzegari
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Impact of Earnings Sustainability and Economic Conditions on Value Relevance of Accounting Information [PDF]

open access: yesپژوهش‌های تجربی حسابداری, 2016
This study demonstrates the impact of earnings sustainability and economic conditions on value relevance of accounting information. The study method is quasi-experimental and the sample consists of firms listed in the Tehran Stock Exchange during the ...
Mahdi Bahar Moghaddam   +1 more
doaj   +1 more source

ANALISIS RELEVANSI NILAI INFORMASI AKUNTANSI SETELAH KONVERGENSI IFRS DI INDONESIA [PDF]

open access: yes, 2016
This study aims to get empirical evidence about the effect of converged International Financial Accounting Standards (IFRS) with PSAK, applicable from 2012 to onwards, to the value relevance of accounting information in Indonesia.
ABDURRAHMAN, Arya, FAISAL, Faisal
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

VALUE RELEVANCE OF INTERNATIONAL FINANCIAL REPORTING STANDARD FOUR OF LISTED NIGERIAN INSURANCE FIRMS

open access: yesGusau Journal of Accounting and Finance, 2022
There is growing concern among regulators and investors over the depreciation in the value of listed insurance firms in Nigeria. The study examines the value relevance of the information content of IFRS 4: Insurance Contracts disclosure of listed ...
Mariya Mohammed Hafiz   +2 more
doaj  

ANALISIS PERBEDAAN RELEVANSI NILAI DAN ASIMETRI INFORMASI SEBELUM DAN SESUDAH KONVERGENSI IFRS PADA PERUSAHAAN MANUFAKTUR DI BURSA EFEK INDONESIA

open access: yesJurnal Akuntansi Kontemporer, 2020
IFRS is an international standard which has two main characteristics, namely fair value and principle based. The use of fair value resulted in financial report’s relevance, which resulting any differences in the value relevance of accounting information.
Cynthia Esterlina, Lindrawati Lindrawati
doaj   +1 more source

Value relevance and changes in accounting standards: A review of the IFRS adoption literature

open access: yesCogent Business & Management, 2022
Share prices reflect available financial information about those firms and a substantial amount of these information come from financial statement figures.
Japhet Imhanzenobe
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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