Results 71 to 80 of about 2,074,348 (318)
Identify and Analysis of Factors Affecting the Success of New Product Development by Using System Dynamics Approach [PDF]
Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2019 The companies for their growth and survival in competitive domains must develop new products; however, innovation required for this process is a risky and costly enterprise.
Tayebeh Abbasnejad +2 more
doaj +1 more source
Management Accounting Education a Challenge in Facing the 21st Century [PDF]
, 1997 Since the beginnig of 1980s, business have been challenged by some problems, such as the keener competition and world-wide competition. The major cause of those problems is the changing business paradigm from producer-driven to customer-driven.
Machfoedz, M. (Mas'ud)
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Distributive Justice in Banking: A Systematic Review of the Literature and Its Approaches for the Iranian Banking System [PDF]
تحقیقات مالی اسلامی (پیوسته)1. Introduction and ObjectiveThe operations of the banking system are intrinsically linked to money creation and credit supply, processes that directly influence the distribution and redistribution of wealth in society.
Mohammad Mahdi Fotouhi Rashidi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Performance Implications of Fit Among Environment, Strategy, Structure, Control System and Social Performance [PDF]
, 2013 Purpose – The paper examined concept of corporate performance. The paper seeks to examine the impact of corporate social performance on the relationship among business environment, strategy, organization, and control system and corporate performance.
Fauzi, Hasan
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Compilation and Validation of a Comprehensive Model of Performance Audit in the Field of Health Using a Fuzzy Delphi Method [PDF]
Taṣvīr-i salāmatBackground. Measuring the efficiency, effectiveness and economic efficiency in the public sector and accordingly allocating resources based on the accepted indicators leads to an increase in public welfare.
Hojjat Esmati Beyrami +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source