Results 41 to 50 of about 908,995 (331)

Economic Aspects Regarding the Development of the Liberal Professions in Romania

open access: yesEIRP Proceedings, 2021
The liberal profession plays an important role in creating added value and profitability in the current economy context of Romania, especially in this time of global health crisis.
Gabriela Marchis
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

PERILAKU PENGGUNA SISTEM INFORMASI AKUNTANSI E-COMMERCE [PDF]

open access: yesJurnal Akuntansi Multiparadigma, 2019
: The Behaviour of E-Commerce Accounting Information System Users. The purpose of this study is conducted to determine a person's behavior using information technology-based financial accounting records in e-commerce.
Erwanda Nuryahya   +2 more
doaj   +1 more source

Developing Resource Usage Service in WLCG [PDF]

open access: yes, 2011
According to the Memorandum of Understanding (MoU) of the World-wide LHC Computing Grid (WLCG) project, participating sites are required to provide resource usage or accounting data to the Grid Operational Centre (GOC) to enrich the understanding of how ...
Chen, Xiaoyu   +3 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Spatial modelling for mixed-state observations

open access: yes, 2008
In several application fields like daily pluviometry data modelling, or motion analysis from image sequences, observations contain two components of different nature.
Hardouin, Cécile, Yao, Jian-Feng
core   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

IMPLEMENTASI PENCATATAN KEUANGAN PADA USAHA KECIL DAN MENENGAH

open access: yesJurnal Ilmiah Bisnis dan Ekonomi Asia, 2018
This study aims to determine the application of financial records on small and medium business units (SMEs) because the SME sector is currently the sector that became the government's flagship.
Pipit Rosita Andarsari, Justita Dura
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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