Results 71 to 80 of about 983,136 (266)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Treinta años de investigación en contabilidad y gestión pública en España
Revista de Contabilidad: Spanish Accounting Review, 2010 El objetivo de este trabajo, que introduce este número especial en Contabilidad Pública, es analizar la evolución de la investigación en esta área en las universidades españolas, dado el proceso de modernización y normalización que la Contabilidad ...
Isabel Brusca
doaj
Large shareholders and accounting research [PDF]
China Journal of Accounting Research, 2012 AbstractLarge shareholders are a potentially very important element of firms’ corporate governance system. Whereas analytical research is typically vague on who these large shareholders are, in practice there are important variations in the types of large owners (and the different types of large owners could play very different governance roles). After
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
La investigación contable pensada desde las estrategias de investigación social-cualitativa
Teuken Bidikay, Revista Latinoamericana de Investigación en Organizaciones Ambiente y Sociedad, 2014 La exploración de nuevos terrenos metodológicos para la investigación contable puede hacerse retomando las alternativas heterodoxas: la corriente interpretativa y la corriente crítica, las cuales pueden resultar prometedoras para enriquecer la ...
Julieth Sorany Alzate Giraldo
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Revista de Contabilidad: Spanish Accounting Review, 2001 En este trabajo se lleva a cabo una revisión de la literatura contable de la última década referida al mercado de capitales. Varias razones explican el interés por este tipo de investigación: es una de las áreas más prolíficas en la investigación ...
Begoña Giner Inchausti
doaj