Results 191 to 200 of about 579,964 (385)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
When Do Green Absorptive Capacity and Ambidextrous Open Innovation Foster Sustainable Performance
Business Strategy and the Environment, EarlyView.ABSTRACT This study aims to assess the relationships between two green absorptive capacities and interorganizational learning measured in terms of ambidextrous open innovation, analyzing firms' sustainable performance within knowledge‐based theoretical frameworks.
Junggeun Kim, Murad Ali, Taewoo Roh
wiley +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Hospital Accreditation Surveyors\' Evaluation Criteria in Iran
پیاورد سلامت, 2019 Background and Aim: Hospital accreditation is an external evaluation strategy used to improve the quality and effectiveness of services. Accreditation surveyors are among the important factors affecting the validity of accreditation results.
Ebrahim Jaafaripooyan +2 more
doaj
Promising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Design and Characterization of Prodrugged Anti‐CTLA‐4 Antibodies
ChemBioChem, Accepted Article.Therapeutic antibodies are widely used to treat diseases like cancer and inflammatory conditions by binding with high specificity to their molecular targets. Masking is a strategy to mitigate undesirable activity in non‐target tissues, improving safety and pharmacokinetic (PK) profiles by reducing target‐mediated drug disposition (TMDD). In this study,
Sayumi Yamazoe +15 more
wiley +1 more source
27 The accreditation process drives rapid quality improvement – continued review is critical
BMJ Open Quality, 2020 Peggy McElgunn, Bonnie Weiner
doaj +1 more source