Results 291 to 300 of about 591,901 (383)

Post‐Mortem Identification and Toxicological Findings of Fluetonitazepyne and Isotonitazepyne

open access: yesDrug Testing and Analysis, EarlyView.
In early 2025, five death cases in Finland tested positive for fluetonitazepyne and one for isotonitazepyne in urine drug screening. A peak corresponding to O‐dealkylated fluetonitazepyne, the 4‐OH‐nitazepyne metabolite, was present in all fluetonitazepyne‐positive urine samples and was later used in the identification of isotonitazepynein one fatal ...
Pirkko Kriikku   +3 more
wiley   +1 more source

Developing global consensus about core knowledge and skills for genetic counselor education. [PDF]

open access: yesJ Genet Couns
McEwen A   +4 more
europepmc   +1 more source

Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers

open access: yesDrug Testing and Analysis, EarlyView.
Exogenous T was detected with IRMS regardless of T/E elevation—high serum T indicative for IRMS. rhEPO was detected in urine for 72 h in ITP and CP, and Tasso showed less sensitivity than previous DBS devices tested. ABSTRACT Doping with testosterone (T) and erythropoietin (EPO) in low doses (micro‐doping) is a challenge to detect.
Carmel Heiland   +5 more
wiley   +1 more source

Long‐Term Stability of Ethyl Glucuronide in Hair: A 10‐Year Retrospective Analysis of 909 Samples by LC–MS/MS

open access: yesDrug Testing and Analysis, EarlyView.
EtG hair analysis has a standard method for detecting alcohol abuse. In this study, we assessed the long‐term stability of EtG in hair stored up to 10 years. A total of 909 samples originally analyzed between 2013 and 2022 were re‐tested in 2023 by LC‐MS/MS.
Sara Casati   +6 more
wiley   +1 more source

Origin and Interpretation of Low Methamphetamine Levels Found in Amphetamine‐Positive Urine Samples: Support for Methylation of Amphetamine as a Minor Metabolic Pathway

open access: yesDrug Testing and Analysis, EarlyView.
A low urinary concentration of methamphetamine less than 1% of the amphetamine level may not necessarily indicate polydrug use. Instead, it could result from N‐methylation of amphetamine. Chiral analysis of both amphetamines is an effective method for distinguishing between illicit use and therapeutic sources in positive drug screening results ...
Anders Helander   +2 more
wiley   +1 more source

Biosynthesis and Identification of Clenbuterol Metabolites in Urine and In Vitro Microsome Incubation Samples Using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometry: A Comparison Between Human and Bovine Metabolism

open access: yesDrug Testing and Analysis, EarlyView.
Clenbuterol metabolism was studied in bovine and human urine using LC‐Q‐Exactive‐Orbitrap MS; eight metabolites were identified in human and bovine samples as well as a novel N‐methylated form. Four urinary metabolites specific to cattle were detected and identified.
Anuar Gómez‐Tagle   +5 more
wiley   +1 more source

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