Results 71 to 80 of about 579,964 (385)

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source

Documenting Successful Experiences of Reorganizing the Hospital and Human Resource Management in an Iranian Referral Hospital During the COVID-19 Pandemic [PDF]

Journal of Evidence-Based Care
Background: Human resource provision in the COVID-19 pandemic crisis is a challenge for nursing managers. The outbreak of the COVID-19 pandemic has made a major challenge of staff for health organizations.Aim: The present study was conducted with aim to ...
Shahpar Dolati, Akram Mojarad, Mansoureh Dimeh Noghani, Marzieh Hedayat, Maliheh Morgan Torqabeh, Zohreh Sezavarmanesh, Hamidreza Jalalzaei, Mohammad-Mehdi Shahabi, Seyed Mahsan Mousavi, Zohre Pouresmail, Fatemeh Heshmati Nabavi   +10 more
doaj   +1 more source

Accreditation or accreditations? A comparative study about accreditation in France, United Kingdom and Cataluña

Revista da Associação Médica Brasileira, 2011
This article analyzes the dynamics and changes in the accreditation process in three different places - France, UK and Cataluña (Spain) - based on documents about their health systems organizations, funding sources and regulations. The objective was to find out about the relevant aspects of the strategies of these countries' institutions that adapted ...
Maria Thereza Ribeiro Fortes, Tatiana Wargas de Faria Baptista, Ruben Araujo de Mattos   +2 more
openaire   +3 more sources

Impact of repeated hospital accreditation surveys on quality and reliability, an 8-year interrupted time series analysis

BMJ Open, 2019
Objective To evaluate whether hospital re-accreditation improves quality, patient safety and reliability over three accreditation cycles by testing the accreditation life cycle model on quality measures.
Subashnie Devkaran, P. O'farrell, S. Ellahham, Randy Arcangel   +3 more
semanticscholar   +1 more source

Enhanced Catalytic Cycle of Glucose Oxidation and Reactive Species with ROS and RHS Generation Mediated by Galvanic Engineering of Dual Atomic Sites on Covalent Organic Frameworks Demonstrating Synergistic Bimetal Tumor Treatment

Advanced Science, EarlyView.
A galvanic replacement is used to control dual atomic metals (Au and Ir) on a covalent organic framework (COF) nanoparticle and then coated with hyaluronic acid (HA). Under a specific bimetallic ratio (COF/Aux/Ir1‐x), the optimization can be achieved for the conversion of intracellular nutrients into reactive species (HOCl and O2• ─) and effectively ...
Wei‐Chung Pan, Cheng‐Hung Luo, Wen‐Ling Lin, Liu‐Chun Wang, Divinah Manoharan, Po‐Ya Chang, Hwo‐Shuenn Sheu, Chen‐Hao Yeh, Chia‐Jui Yen, Chen‐Sheng Yeh   +9 more
wiley   +1 more source

Enhancing the capabilities of biosafety laboratories through the established accreditation system: Development of the biosafety laboratory accreditation system in China

Journal of Biosafety and Biosecurity, 2019
Accreditation is now widely used to attest for laboratory competence. Although accreditation was originally used to assess products in testing laboratories and still plays an increasingly important role in international trade, it has been expanded to ...
Peijun Zhai, Rong Wang, Yongyun Zhou, Dongmei Hu, Junyan li, Yali Zhou   +5 more
doaj  

Chest Pain Center Accreditation Is Associated With Improved In‐Hospital Outcomes of Acute Myocardial Infarction Patients in China: Findings From the CCC‐ACS Project

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Chest pain center (CPC) accreditation plays an important role in the management of acute myocardial infarction (AMI). However, no evidence shows whether the outcomes of AMI patients are improved with CPC accreditation in China.
F. Fan, Yuxi Li, Yan Zhang, Jianping Li, Jing Liu, Y. Hao, Sidney C. Smith, G. Fonarow, K. Taubert, J. Ge, Dong Zhao, Y. Huo   +11 more
semanticscholar   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Comparison between two accreditation criteria: A report on the differences between the IFOAM Accreditation Criteria and ISO 65 (EN 45011) [PDF]

, 2003
The paper describes the results of a comparison between two accreditation criteria: the IFOAM Accreditation Criteria and ISO 65 (EN 45011. The comparison does not provide an assessment of each norm, and the format of the comparison makes it difficult ...
Huber, Beate
core  

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source