Results 141 to 150 of about 12,584 (243)

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

iMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui, Jiameng Li, Caifeng Li, Mo Sun, Wei Liu, Xuxia Cao, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen   +9 more
wiley   +1 more source

Building India's Low-Carbon Healthcare System: A Comprehensive Review of National Policies, Operational Frameworks, and Decarbonization Strategies. [PDF]

Ann Glob Health
Thirumoorthi H, Pape Reddy SS.
europepmc   +1 more source

Growing Demand and Uneven Supply: Eight Years of Nature Education in China 需求增长与供给不均:中国自然教育八年发展回顾

Integrative Conservation, EarlyView.
ABSTRACT This study examines the role of nature education in advancing conservation and sustainability in China between 2014 and 2023. Drawing on national survey reports and historical–comparative methods, it analyses the dynamics of public demand, institutional supply, and practitioner capacity.
Qi Yunxi, Lyu Xiang, Huang Yu
wiley   +1 more source

Preparing for the future of medical education over the next five years: the key recommendations of an expert panel. [PDF]

Int J Med Educ
Zaid S, Hassan S, Sandars J, Baloch H, Zehra T, Mirzazadeh A, Patricio M.   +6 more
europepmc   +1 more source

Achieving superior therapeutic effects on methicillin‐resistant Staphylococcus aureus infection via simple sulfonation process for preparing zwitterionic photosensitizer

Interdisciplinary Medicine, EarlyView.
The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu, Yin Li, Qiyun Deng, Ruixin Guo, Yu Huang, Wenyan Guo, Xi Chen, Ben Zhong Tang, Zhiming Wang, Lidan Chen, Zhaohui Sun   +10 more
wiley   +1 more source

Educational Commission for Foreign Medical Graduates (ECFMG) Accreditation Policy Change: A Boon or Setback for Caribbean Medical Schools? [PDF]

Adv Med Educ Pract
Arja SB, Chundru P.
europepmc   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

The invisible crisis facing forensic providers in the United States. [PDF]

Forensic Sci Int Synerg
europepmc   +1 more source

Reducing STEMI Treatment Delays: A Quality Improvement Project at a Rural Community Hospital. [PDF]

JACC Case Rep
Langenhorst S.
europepmc   +1 more source

Deliberate Practice Supervision to Enhance the Effectiveness of Behavioral Activation for Depression: A Case Study

Journal of Clinical Psychology, Volume 81, Issue 6, Page 526-537, June 2025.
ABSTRACT Deliberate Practice (DP) is a model of behavioral skill acquisition structured by several key tasks. The past decade has shown a consistent growth in interest in this form of learning for psychotherapy skills, with promising research suggesting DP training is superior to traditional learning methods of psychotherapy. This paper presents a case
Dan Sacks
wiley   +1 more source