Results 91 to 100 of about 609 (248)

Coordinated space-and ground-based monitoring of accretion bursts in a protoplanetary disc: The orbital and accretion properties of DQ Tau★

Astronomy & Astrophysics
Multiplicity in pre-main-sequence (PMS) systems shapes circumstellar and circumbinary discs, often resulting in morphological features such as inner cavities, spiral arms, and gas streamers that facilitate mass transfer between the disc and stars ...
Alqubelat Hala, Manara Carlo F., Campbell-White Justyn, Petr-Gotzens Monika G., Tofflemire Benjamin M., Banzatti Andrea, Ragusa Enrico, Whelan Emma T., Bourdarot Guillaume, Dougados Catherine, Fiorellino Eleonora, Mills Sean I.   +11 more
doaj   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

THREE-DIMENSIONAL NUMERICAL HYDRODYNAMICAL SIMULATION OF LOW/HARD AND HIGH/SOFT STATES IN ACCRETION DISCS OF MICROQUASARS AND QUASARS ON BASE OF UNDEFINED PRECESSION

Odessa Astronomical Publications, 2016
In this study, the models of slaved precession of accretion disc and donors radiationdriven wind were performed using three-dimensional numerical astrophysical methods by the example of microquasar Cyg X-1. As is shown, in the course of precession of the
V. V. Nazarenko, S. V. Nazarenko
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Astrometric view of companions in the inner dust cavities of protoplanetary discs

Astronomy & Astrophysics
Context. Protoplanetary discs with inner dust cavities (often referred to as ‘transition discs’) are potential signposts of planet formation. However, few companions have been identified within these cavities, and the role of companions in shaping them ...
Vioque Miguel, Booth Richard A., Ragusa Enrico, Ribas Álvaro, Kurtovic Nicolás T., Rosotti Giovanni P., Penoyre Zephyr, Facchini Stefano, Garufi Antonio, Manara Carlo F., Huélamo Nuria, Winter Andrew, Pérez Sebastián, Benisty Myriam, Mendigutía Ignacio, Cuello Nicolás, Penzlin Anna B. T., Castro-Ginard Alfred, Teague Richard   +18 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Transition to magnetorotational turbulence in Taylor–Couette flow with imposed azimuthal magnetic field

New Journal of Physics, 2015
The magnetorotational instability (MRI) is thought to be a powerful source of turbulence and momentum transport in astrophysical accretion discs, but obtaining observational evidence of its operation is challenging.
A Guseva, A P Willis, R Hollerbach, M Avila   +3 more
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

Dust dynamics in planet-forming discs in binary systems. [PDF]

Eur Phys J Plus, 2023
Zagaria F, Rosotti GP, Alexander RD, Clarke CJ.   +3 more
europepmc   +1 more source