Results 211 to 220 of about 6,700,738 (247)

Revisiting lupus low disease activity: validation matters, but vindication is imperative. [PDF]

Rheumatology (Oxford)
Parodis I.
europepmc   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Sarcopenic obesity and skeletal development in children: recent advances. [PDF]

Front Pediatr
Liu Y, Li X, Liu X.
europepmc   +1 more source

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

Bevacizumab plus iparomlimab/tuvonralimab with hepatic artery infusion chemotherapy followed by stereotactic body radiotherapy in patients with BCLC stage C hepatocellular carcinoma with thrombus and/or extrahepatic oligometastases (BITS-TO-HCC): study protocol of a prospective, single-center, single-arm, phase II study. [PDF]

Ther Adv Med Oncol
Liu Y, Wang H, Zhu K, Jiang S, Shi F, Feng R, Dou X, Xu L, Gong Z, Wang S, Wang C, Wang P, Zhang X, Yue J.   +13 more
europepmc   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

Epilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Systemic Lupus International Collaborating Clinics Frailty Index predicts mortality in systemic lupus erythematosus patients: data from the Almenara Lupus Cohort. [PDF]

Lupus Sci Med
Rashuamán-Conche BH, Gamboa-Cárdenas RV, Pimentel-Quiroz VR, Singh A, Reátegui-Sokolova C, Elera-Fitzcarrald C, Garcia-Hirsh S, Pastor-Asurza C, Rodríguez-Bellido Z, Perich-Campos RA, Alarcón GS, Ugarte-Gil MF.   +11 more
europepmc   +1 more source

Phenotypic and transcriptomic characterization of biallelic RNU2‐2 developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Abstract Objective A significant proportion of individuals with suspected genetic developmental and epileptic encephalopathies (DEEs) remain unsolved following whole genome sequencing (WGS). Here we describe biallelic RNU2‐2 variants causing a recently reported, severe, recessive DEE.
Olivia J. Henry, Nadja Pekkola Pacheco, Irene Duba, Magnus Burstedt, Daniel Carlberg, Angelica M. Delgado‐Vega, Anna Hammarsjö, Sofie Ivarsson, Tord Jonson, Kristina Karrman, Nicole Lesko, Åsa Lindfors, Daniel Nilsson, Mia Olsson Engman, Lucía Peña‐Pérez, Erik Stenund, Fulya Taylan, Malin Ueberschär, Samuel Wiafe, Sofia Ygberg, Anna Lindstrand, Anna Wedell, Ann Nordgren, Tommy Stödberg   +23 more
wiley   +1 more source

Short-term effects of ocrelizumab on cortical pathology in patients with multiple sclerosis. [PDF]

Neurotherapeutics
Cavalli N, Boffa G, Cipriano E, Boccia VD, Al Qudsi S, Baldisseri F, Leveraro E, Nasone L, Magon S, Cellerino M, Inglese M, Lapucci C.   +11 more
europepmc   +1 more source

Validation of proposals for definitions of moderate and severe disease activity in SLE: impact on flares, quality of life, damage accrual, hospitalisations and mortality. [PDF]

Lupus Sci Med
Altabás-González I, Rua-Figueroa I, Roberts K, Mamani IL, Mouriño C, Martinez-Barrio J, Galindo Izquierdo M, Calvo-Alén J, Erausquin C, Serrano-Benavente B, Uriarte E, Tomero E, Freire-González M, Blanco R, Salgado E, Gómez-Sabater S, Fernandez-Nebro A, Sangüesa C, Narvaez J, Mena Vázquez N, Menor-Almagro R, Rosas Gómez de Salazar JC, Aurrecoechea E, Ibarguengoitia-Barrena O, Montilla C, Bonilla G, Segarra VT, Juan-Mas A, García-Villanueva MJ, Morales CM, Horcada L, Lozano-Rivas N, Iñiguez C, Arevalo M, Paredes B, Exposito L, Toyos FJ, Flores-Fernandez E, Nóvoa Medina J, Fragio Gil JJ, Bohórquez C, Pego-Reigosa JM.   +41 more
europepmc   +1 more source