Results 51 to 60 of about 159,034 (217)
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
accuMUlate: a mutation caller designed for mutation accumulation experiments [PDF]
Bioinformatics, 2017 Abstract Summary Mutation accumulation (MA) is the most widely used method for directly studying the effects of mutation. By sequencing whole genomes from MA lines, researchers can directly study the rate and molecular spectra of spontaneous mutations and use these results to understand how ...
David J. Winter +5 more
openaire +2 more sources
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
, 2022 A typestate specification indicates which behaviors of an object are permitted in each of the object’s states. In the general case, soundly checking a typestate specification requires precise information about aliasing (i.e., an alias or pointer analysis), which is computationally expensive. This requirement has hindered the adoption of sound typestate
Martin Kellogg +3 more
openaire +3 more sources
An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology
Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos +2 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
Performances of cryptographic accumulators [PDF]
39th Annual IEEE Conference on Local Computer Networks, 2014 Cryptographic accumulators are space/time efficient data structures used to verify if a value belongs to a set. They have found many applications in networking and distributed systems since their in- troduction by Benaloh and de Mare in 1993. Despite this popularity, there is currently no performance evaluation of the different existing de- signs ...
Kumar, Amrit +2 more
openaire +2 more sources
Journal of Marine Science and Engineering, 2019 Faults have complex internal structures, which can be divided into the fault core and the damaged zone. During the fault formation process, the damaged zone will develop a large number of fractures cross cutting the adjacent host rocks, where the size ...
Ru Jia +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa +7 more
wiley +1 more source