Results 131 to 140 of about 84,610 (332)

Technical and economic analysis of the use of mobile charging stations for electric vehicles in the Republic of Tajikistan

open access: yesИнтеллект. Инновации. Инвестиции
The global electric vehicle market is increasing. The main motivation for switching to this innovative type of vehicle is, first of all, reducing the impact on the environment, reducing operating costs, the possibility of using new technologies in ...
 Abdullo Mamadamon
doaj   +1 more source

Searching for Antiproton Decay at the Fermilab Antiproton Accumulator

open access: yes, 1995
This paper describes an experimental search for antiproton decay at the Fermilab Antiproton Accumulator. The E868 (APEX) experimental setup is described.
Geer, S.
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Application of the Hydraulic Accumulator Technology on the RFID Sleeve

open access: yesShiyou jixie, 2016
The existed common fracturing sleeves have the technological issues like restricted fracturing stages,unachieved full bore of string,frequent tripping of switching tool.To address the issues,the possible application of hydraulic accumulator technology on
Zhao Chenxi, Dai Wenchao, Qin Jinli
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Technical Benefits of Tram Vehicle Energy Accumulator

open access: yesAdvances in Electrical and Electronic Engineering, 2004
Energy saving effects connected with use of energy accumulator on board of tram vehicle instead of substation are presented. Differences in results regarding weak and strong power supply system when taking into account energy losses and energy ...
Tadeusz Maciolek, Zbigniew Drazek
doaj  

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