Results 91 to 100 of about 9,094,622 (309)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Google Earth elevation data extraction and accuracy assessment for transportation applications
PLoS ONE, 2017 Roadway elevation data is critical for a variety of transportation analyses. However, it has been challenging to obtain such data and most roadway GIS databases do not have them.
Yinsong Wang +5 more
semanticscholar +1 more source
Remote Sensing, 2015 Land cover change processes are accelerating at the regional to global level. The remote sensing community has developed reliable and robust methods for wall-to-wall mapping of land cover changes; however, land cover changes often occur at rates below ...
Heinz Gallaun +5 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Accuracy Assessment of Digital Surface Models from Unmanned Aerial Vehicles' Imagery on Glaciers
Remote Sensing, 2017 The use of Unmanned Aerial Vehicles (UAV) for photogrammetric surveying has recently gained enormous popularity. Images taken from UAVs are used for generating Digital Surface Models (DSMs) and orthorectified images.
S. Gindraux, R. Boesch, D. Farinotti
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Good Practices for Object-Based Accuracy Assessment
Remote Sensing, 2017 Thematic accuracy assessment of a map is a necessary condition for the comparison of research results and the appropriate use of geographic data analysis.
J. Radoux, P. Bogaert
semanticscholar +1 more source
Free European data on forest distribution: overview and evaluation
Journal of Forest Science, 2013 A growing need for the evaluation of prospects and sustainability of forest resources calls for the availability of harmonized data on forest distribution.
J. Trombik, T. Hlásny
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source