Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Dimensional Accuracy Assessment of 3D-Printed Edentulous Jaw Models: A Comparative Analysis Using Three Laboratory Scanners. [PDF]
Yanakiev S, Dimova-Gabrovska M.
europepmc +1 more source
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Spatial and Temporal Field-Scale Accuracy Assessment of a Multi-Sensor Spade for In Situ Soil Diagnostics: Performance and Limitations of the Stenon FarmLab for Precision Agriculture. [PDF]
Grenzdörffer GJ, Wienken JS, Steiger A.
europepmc +1 more source
Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu +7 more
wiley +1 more source
Fit accuracy assessment of removable partial denture frameworks produced by direct metal laser sintering - a clinical trial. [PDF]
Conceição PR +4 more
europepmc +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Accuracy assessment of digital impressions with varied scanning paths in partially edentulous ridges with mobile abutment teeth: An in vitro comparative study. [PDF]
Alaghbari SS +8 more
europepmc +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Comparative Accuracy Assessment of Large Language Models in Cardiothoracic Anesthesia: A Performance Analysis of Claude and ChatGPT-4 on Subspecialty Board-Style Questions. [PDF]
Beil J, Aggarwal I, Devarapalli M.
europepmc +1 more source

