Results 61 to 70 of about 1,255,495 (313)
Collaborative validation of GlobeLand30: Methodology and practices
30-m Global Land Cover (GLC) data products permit the detection of land cover changes at the scale of most human land activities, and are therefore used as fundamental information for sustainable development, environmental change studies, and many other ...
Jun Chen +9 more
doaj +1 more source
Accuracy of a multiport network analyzer [PDF]
The accuracy of a multiport vector network analyzer, which uses a new calibration concept, has been compared with a 2-port network analyzer that implements the classical TRL procedure.
F. SAMPIETRO +9 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Assessment of Consensus Forecasts Accuracy: The Czech National Bank Perspective [PDF]
Consensus Economics forecasts for euro-area GDP growth, consumer and producer price inflation and the USD/EUR exchange rate are used by the Czech National Bank to make assumptions about future external economic developments.
Filip Novotny, Marie Rakova
core +2 more sources
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Ground Truth in Classification Accuracy Assessment: Myth and Reality
The ground reference dataset used in the assessment of classification accuracy is typically assumed implicitly to be perfect (i.e., 100% correct and representing ground truth).
Foody, Giles M., Giles M. Foody
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Assessing the Accuracy of Diagnostic Tests.
Gold standard tests are usually used for diagnosis of a disease, but the gold standard tests may not be always available or cannot be administrated due to many reasons such as cost, availability, ethical issues etc. In such cases, some instruments or screening tools can be used to diagnose the disease. However, before the screening tools can be applied,
LI, Fangyu, HE, Hua
openaire +2 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

