Results 61 to 70 of about 3,003,896 (307)

Inter-Comparisons of Daily Sea Surface Temperatures and In-Situ Temperatures in the Coastal Regions

open access: yesRemote Sensing, 2020
In this study, seven, global, blended, sea surface temperature (SST) analyses, including Operational SST and Sea Ice Analysis (OSTIA), Canadian Meteorological Centre (CMC) analysis, Optimum Interpolation SST (OISST), Remote Sensing System (REMSS ...
Hye-Jin Woo, Kyung-Ae Park
doaj   +1 more source

Accuracy Assessment of a UAV Direct Georeferencing Method and Impact of the Configuration of Ground Control Points

open access: yesDrones, 2022
Unmanned aerial vehicles (UAVs) can obtain high-resolution topography data flexibly and efficiently at low cost. However, the georeferencing process involves the use of ground control points (GCPs), which limits time and cost effectiveness.
Xiaoyu Liu   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

High resolution satellite imagery orientation accuracy assessment by leave-one-out method: accuracy index selection and accuracy uncertainty [PDF]

open access: yes, 2008
The Leave-one-out cross-validation (LOOCV) was recently applied to the evaluation of High Resolution Satellite Imagery orientation accuracy and it has proven to be an effective method alternative with respect to the most common Hold-out-validation (HOV),
CRESPI, Mattia Giovanni   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Collaborative validation of GlobeLand30: Methodology and practices

open access: yesGeo-spatial Information Science, 2021
30-m Global Land Cover (GLC) data products permit the detection of land cover changes at the scale of most human land activities, and are therefore used as fundamental information for sustainable development, environmental change studies, and many other ...
Jun Chen   +9 more
doaj   +1 more source

Perturbative operator approach to high-precision light-pulse atom interferometry

open access: yes, 2020
Light-pulse atom interferometers are powerful quantum sensors, however, their accuracy for example in tests of the weak equivalence principle is limited by various spurious influences like magnetic stray fields or blackbody radiation.
Giese, Enno, Ufrecht, Christian
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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