Results 41 to 50 of about 1,460,902 (312)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
On the recovery of a function on a circular domain
, 2002 We consider the problem of estimating a function f (x, y) on the unit disk {(x, y): x(2) -l- y(2) less than or equal to 1}, given a discrete and noisy data recorded on a regular square grid.
Pawlak, M, Liao, SX
core +1 more source
Journal of Information and Organizational SciencesA finite zero-sum game defined on a subset of the unit square is considered. The game is a generalized progressive discrete silent duel, in which the kernel is skew-symmetric, and the players, referred to as duelists, have identical linear accuracy ...
Vadim Romanuke
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Effects of steady state free precession parameters on cardiac mass, function, and volumes. [PDF]
, 2007 PURPOSE: We aimed to investigate comparability of LV volumes, function, and mass acquired with three steady-state free precession (SSFP) pulse sequences, simulating typical vendor and protocol specific differences in data acquisition. METHODS: Twenty-one
Francis, JM +7 more
core +1 more source
应用气象学报, 2020 Profiles of atmospheric temperature and water vapor are important for studying atmospheric state and play an important role in the energy balance of earth-atmosphere system.
Zong Xuemei
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The eGFR-C study: accuracy of glomerular filtration rate (GFR) estimation using creatinine and cystatin C and albuminuria for monitoring disease progression in patients with stage 3 chronic kidney disease - prospective longitudinal study in a multiethnic population [PDF]
, 2014 Background: Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority populations.
Sutton, AJ +80 more
core +1 more source
Membership Score of an Interval-Valued Pythagorean Fuzzy Numbers and Its Applications
IEEE Access, 2023 The main aim of the paper is to define a new Membership score function on the class of interval-valued Pythagorean fuzzy numbers, which can overcome the drawbacks of existing familiar ranking methods.
Melfi A. Alrasheedi, S. Jeevaraj
doaj +1 more source
Evaluating the accuracy of a functional SNP annotation system [PDF]
BMC Bioinformatics, 2009 Many common and chronic diseases are influenced at some level by genetic variation. Research done in population genetics, specifically in the area of single nucleotide polymorphisms (SNPs) is critical to understanding human genetic variation. A key element in assessing role of a given SNP is determining if the variation is likely to result in change in
Terry H. Shen +2 more
openaire +2 more sources