Results 121 to 130 of about 29,072 (293)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Neither agreement nor pronouns

open access: yesIsogloss
Baker & Kramer (2018) suggests that the distribution of clitic doubling in Spanish follows from Weak Crossover. Thus, the fact that in accusative clitic doubling bare wh-phrases cannot be doubled (e.g., *¿A quién lo viste?
Andrés Saab
doaj   +1 more source

Counting markedness : a corpus investigation on German free relative constructions [PDF]

open access: yes, 2004
This paper reports the results of a corpus investigation on case conflicts in German argument free relative constructions. We investigate how corpus frequencies reflect the relative markedness of free relative and correlative constructions, the relative ...
Vogel, Ralf, Zugck, Marco
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

What secondary predicates in russian tell us about the link between tense, aspect and case [PDF]

open access: yes, 2013
In this paper I show that the different case marking possibilities on predicate adjectives in depictive secondary predicates in Russian constitute the uninterpretable counterpart of the interpretable tense and aspect features of the adjective.
Richardson, Kylie
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Why is German dependency parsing more reliable than constituent parsing? [PDF]

open access: yes, 2006
In recent years, research in parsing has extended in several new directions. One of these directions is concerned with parsing languages other than English.
Kübler, Sandra, Prokic, Jelena
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Indo-Uralic and Altaic [PDF]

open access: yes, 2010
Elsewhere I have argued that the Indo-European verbal system can be understood in terms of its Indo-Uralic origins because the reconstructed Indo-European endings can be derived from combinations of Indo-Uralic morphemes by a series of well-motivated ...
Kortlandt, Frederik H. H.
core  

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