Results 71 to 80 of about 29,072 (293)
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Glossa, 2017 The traditional notion of case is too coarse to distinguish between the English prepositional dative and the English shifted dative, the Spanish bare accusative and the Spanish “a” accusative, etc.
Michal Starke
doaj +2 more sources
Expressing possession with HAVE and BE: affected possession structures in Flemish [PDF]
, 2015 This paper concerns a cartographic account of Flemish Event Possessives (FEVPs) which alternate between a variety with HAVE and one with BE. The FEVP matrix subjects have the interpretation of both being the Possessor (in its broadest meaning) of the ...
Buelens, Liisa
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Prepositions in Modern Greek: Accusative or genitive case? [PDF]
Zbornik Radova Filozofskog Fakulteta u PrištiniPrepositions are indeclinable words with limited lexical meaning that cannot stand alone but can govern one or more cases. In Modern Greek, which has four cases (nominative, genitive, accusative, and vocative), prepositions are commonly used to express a
Baćić-Ćosić Maja G. +1 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Naturalness: some synchronic data of Old Indian
Linguistica, 2011 The framework of the paper is Natural Syntax initiated by Janez Orešnik in thetradition of (morphological) naturalness as established by Wolfgang U. Dressler and Willi Mayerthaler.
Varja Cvetko-Orešnik
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
An active analysis of Basque ergativity
Fontes Linguae Vasconum, 1999 Previous generative work on Basque syntax has attempted to equate either the NOR or the NORK case in Basque with a “subject case” corresponding structurally to nominative.
Arthur Holmer
doaj +1 more source
Linguistic argumentation and logic: An alternative method approach in Arabic grammar [PDF]
, 2013 Rozprawa podkreśla związek między językową argumentacją a logiką. Argumentacja językowa jest systemem językowym, który stosuje znaczenie wyrażeń ujętych w zdania do zarysowania pełnego znaczenia zdań, w nich bowiem konstytuują się zależności między ...
Yaacob, Solehah
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