Results 191 to 200 of about 132,338 (329)

Chronic Cerebral Hypoxia and Cognitive Impairment: A Systematic Review and Meta‐Analysis Based on Chronic Mountain Sickness, Anemia, Chronic Obstructive Pulmonary Disease, and Obstructive Sleep Apnea

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Meta‐analysis of 41 studies revealed chronic hypoxia in conditions such as chronic mountain sickness, anemia, COPD, and OSA significantly increases the risk of cognitive impairment. Shared mechanisms include mitochondrial dysfunction and neuroinflammation, while unique pathways such as erythrocytosis‐induced hyperviscosity and gut–lung–brain axis ...
Haishi Fei, Guirong Cheng, Yan Zeng, Feibo Zhao, Zhichao He, Shengzhong Yi   +5 more
wiley   +1 more source

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function [PDF]

, 2020
Emma S. Winkler, Adam L. Bailey, Natasha M. Kafai, Sharmila Nair, Broc T. McCune, Jinsheng Yu, Julie M. Fox, Rita E. Chen, James T. Earnest, Shamus P. Keeler, Jon H. Ritter, Liang‐I Kang, Sarah Dort, Annette Robichaud, Richard D. Head, Michael J. Holtzman, Michael Diamond   +16 more
openalex   +1 more source

In silico analysis of ACE2 from different animal species provides new insights into SARS-CoV-2 species spillover [PDF]

, 2023
Felipe Pantoja Mesquita, Pedro Filho Noronha Souza, Dyane Rocha Aragão, Expedito Maia Diógenes, Emerson Lucena da Silva, Jackson L. Amaral, V. N. Freire, Débora de Souza Collares Maia Castelo‐Branco, Raquel Carvalho Montenegro   +8 more
openalex   +1 more source

ACE2 Gene [PDF]

, 2020
openaire   +1 more source

Co‐Culture Systems to Study Epithelial‐Immune Interactions During SARS‐CoV‐2 Infection

Current Protocols, Volume 6, Issue 4, April 2026.
Abstract Robust inflammatory responses to viral infection are mediated by immune cell populations, including monocytes and dendritic cells. However, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) does not replicate efficiently in these cell types and instead preferentially infects epithelial cell subsets in the airway.
Scott H. Randell, Katherine C. Barnett
wiley   +1 more source

FP464DELETION OF ACE2 GENE IMPAIRS GLUCOSE HOMEOSTASIS IN NOD MICE [PDF]

, 2015
Heleia Roca-Ho, Marta Riera, Marta Rebull, Julio Pascual, Ma José Soler   +4 more
openalex   +1 more source

Gene Expression Analysis of ACE2, TMPRSS2, and LZTFL1 in COVID-19 Patients: a pilot study [PDF]

Faten Saad, Moustafa Sakr, Hisham Ismail, Ahmed Daif   +3 more
openalex   +1 more source

ACE2 – das missbrauchte Multitalent [PDF]

Der Nephrologe, 2020
openaire   +1 more source

A white‐tailed deer population in Tennessee is unlikely a reservoir for SARS‐CoV‐2, despite multiple exposures

Ecosphere, Volume 17, Issue 4, April 2026.
Abstract A foundational challenge in disease ecology is understanding how pathogens invade and persist on spatiotemporally heterogeneous landscapes. For example, SARS‐CoV‐2 (SCV2) is a viral pathogen of importance to human health that can also infect wildlife.
Mark Q. Wilber, Justin R. Kosiewska, Jeffery C. Chandler, Billy J. Gardner, Dailee Metts, Cameron G. Mitchell, Yun Tao, Grete Wilson‐Henjum, Jacob D. Wyrick, Kim M. Pepin, Dan Grove, Lisa I. Muller   +11 more
wiley   +1 more source

Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased Transmissibility

, 2021
Hin Hark Gan, Alan Twaddle, Benoı̂t Marchand, Kristin C. Gunsalus   +3 more
openalex   +1 more source