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ACE2 and Diabetic Complications
Current Pharmaceutical Design, 2007Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin system (RAS) and converts angiotensin (Ang) I to the vasoconstrictor Ang II, which is thought to be responsible for most of the physiological and pathophysiological effects of the RAS.
Rachael G, Dean, Louise M, Burrell
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Dimeric ACE2-FC Is Equivalent to Monomeric ACE2 in the Surrogate Virus Neutralization Test
Biochemistry (Moscow), 2023Angiotensin converting enzyme 2 (ACE2) is the main cellular receptor for the dangerous sarbecoviruses SARS-CoV and SARS-CoV-2. Its recombinant extracellular domain is used to monitor the level of the protective humoral immune response to a viral infection or vaccine using a surrogate virus neutralization test (sVNT).
Denis E, Kolesov +3 more
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Folia Pharmacologica Japonica, 2022
In the renin-angiotensin system (RAS), angiotensin II (AngII) converted by angiotensin converting enzyme (ACE) exerts a strong physiological activity via the AT1 receptor (AT1R). Thus, the ACE-AngII-AT1R axis positively regulates RAS. On the other hand, angiotensin converting enzyme 2 (ACE2) is known to negatively regulate RAS by degrading AngII into ...
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In the renin-angiotensin system (RAS), angiotensin II (AngII) converted by angiotensin converting enzyme (ACE) exerts a strong physiological activity via the AT1 receptor (AT1R). Thus, the ACE-AngII-AT1R axis positively regulates RAS. On the other hand, angiotensin converting enzyme 2 (ACE2) is known to negatively regulate RAS by degrading AngII into ...
openaire +2 more sources
2019
This paper proposes a new taxonomy of video-game players: the ACE2 model. Building upon related work in player taxonomies, the ACE2 model sets out to refine the established Bartle’s taxonomy of player types by incorporating the aspect of creation play (e.g., as exhibited in modern games such as Minecraft), thereby rendering the refined model more ...
van Dam, Thomas, Bakkes, Sander
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This paper proposes a new taxonomy of video-game players: the ACE2 model. Building upon related work in player taxonomies, the ACE2 model sets out to refine the established Bartle’s taxonomy of player types by incorporating the aspect of creation play (e.g., as exhibited in modern games such as Minecraft), thereby rendering the refined model more ...
van Dam, Thomas, Bakkes, Sander
openaire +1 more source
Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species
Cell, 2021Peipei Du, Pengcheng Han, Lili01 Wu
exaly
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Cell, 2020Qihui Wang, Sheng Niu, Guang-Wen Lu
exaly