LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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ACE-Inhibitory Peptides from Yanbian Cattle Hemoglobin: Screening, Kinetics, and Molecular Dynamics Simulation. [PDF]
Yang S +12 more
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Solvent alternation of the antimicrobial, antioxidant, anticancer activities and chemical profiles of Trametes hirsuta (Wulfen) Lloyd. [PDF]
Ahmed YM +3 more
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Isolation, Purification, Identification, and In Vitro ACE Inhibitory Activity of Tyrosine-Arginine Dipeptide From Red Millet Huangjiu. [PDF]
Li J, Zhong J, Zhang X.
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Innovative discovery and validation of ACE-inhibitory peptides from eggshell membrane keratin byproducts: An integrated computational and <i>in vitro</i> approach. [PDF]
Xu T +6 more
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The In Vitro Multifaceted Biological Activity of Catechins in Relation to Their Oxidation Potentials. [PDF]
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Myocardial perfusion and ACE inhibition.
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ACE inhibition and atherogenesis
Canadian Journal of Physiology and Pharmacology, 2002Recent clinical studies such as HOPE, SECURE, and APRES show that angiotensin-converting enzyme (ACE) inhibitors like ramipril improve the prognosis of patients with a high risk of atherothrombotic cardiovascular events. Atherosclerosis, as a chronic inflammatory condition of the vascular system, can turn into an acute clinical event through the ...
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Cardiac Effects of ACE Inhibition
Journal of Cardiovascular Pharmacology, 1993Hypertension frequently is associated with a number of changes in heart structure and function, such as left ventricular hypertrophy, disturbed diastolic function, and subnormal stroke volume during exercise. Most of these changes probably are related to myocardial fibrosis.
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Clinical Pharmacology of ACE Inhibition
Cardiology, 2008The radioimmunological determinations of immunoreactive ‘angiotensin IF do not truly reflect angiotensin-(l-8)octapeptide levels, and thus cannot provide an accurate reflection of the efficacy of angiotensin-converting enzyme (ACE) inhibition. Elaborate methods are necessary to measure specifically the octapeptide angiotensin II.
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