Spirapril – a modern ACE inhibitor
Кардиоваскулярная терапия и профилактика, 2005 An ACE inhibitor, spirapril, is widely used in modern cardiology practice. Its pharmacokinetics is characterized by prolonged elimination half-life, >24 hours. There is no need for dose titration, even in patients with chronic renal failure.
V. M. Gorbunov
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Cough Syncope due to ACE Inhibitor
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015 Syncope is defined as a transient loss of consciousness due to sudden temporary decline in cerebral perfusion. Cough syncope is classically seen in middle aged obese men with obstructive pulmonary disease.
Filiz Koc +2 more
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A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensisn l-converting enzyme (ACE) unlinked to the ACE gene [PDF]
, 2008 Background: angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on ...
Amy Luke +20 more
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Difference in blood pressure response to ACE-Inhibitor monotherapy between black and white adults with arterial hypertension: a meta-analysis of 13 clinical trials. [PDF]
, 2013 BACKGROUND: Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Africa. The treatment of hypertension
Luke R Smart +13 more
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Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial [PDF]
, 2014 <br>Background: Loss of muscle mass and strength with ageing is a major cause for falls, disability, and morbidity in older people. Previous studies have found that angiotensin-converting enzyme inhibitors (ACEi) may improve physical function in ...
Sumukadas, Deepa +8 more
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Рациональная фармакотерапия в кардиологии, 2016 The main trails proven angiotensin converting enzyme (ACE) inhibitor effects on the life prognosis after myocardial infarction (MI) are described. Different tactics of ACE inhibitors therapy in post MI patients are presented.
S. Yu. Martsevich
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ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). [PDF]
PLoS ONE, 2011 OBJECTIVES: We tested whether angiotensin converting enzyme (ACE) and phosphorylation of Ser(1270) are involved in shear-stress (SS)-induced downregulation of the enzyme.
Valerio Garrone Barauna +3 more
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Captopril-Associated Cough Is Not due to Increased Airway Responsiveness
Canadian Respiratory Journal, 1994 BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors commonly cause cough. There is controversy as to whether preexisting airway hyperresponsivencss predisposes patients to ACE inhibitor-induced cough and whether ACE inhibitor therapy can cause ...
SP Blackie +4 more
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PLoS Medicine, 2016 BackgroundMedications aimed at inhibiting the renin-angiotensin system (RAS) have been used extensively for preventing cardiovascular and renal complications in patients with diabetes, but data that compare their clinical effectiveness are limited.
Ferrán Catalá-López +11 more
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Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2 [PDF]
, 2009 Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is great interest in the therapeutic benefit for ACE2 overexpression in the heart.
Smith, Godfrey +12 more
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