Results 131 to 140 of about 96,770 (285)

Adverse effects in randomized controlled trials comparing angiotensin receptor antagonists and ACE inhibitors versus ACE inhibitors alone in patients with heart failure.

, 2013
Adverse effects in randomized controlled trials comparing angiotensin receptor antagonists and ACE inhibitors versus ACE inhibitors alone in patients with heart failure.
Inder Anand (365855), Gregory Arutiunov (365856), Andrea Kuenzli (365854), Rizwan Afzal (365859), Leo C. Kum (365857), Robert McKelvie (365858), Heiner C. Bucher (134728), Michel White (303419), Alain J. Nordmann (365860)   +8 more
core   +1 more source

Comparative estimation of the effects of antihypertensive medications on schizophrenia occurrence: a multinational observational cohort study

BMC Psychiatry
Background The association between antihypertensive medication and schizophrenia has received increasing attention; however, evidence of the impact of antihypertensive medication on subsequent schizophrenia based on large-scale observational studies is ...
Dong Yun Lee, Chungsoo Kim, Jiwoo Kim, Jeongwon Yun, Yujin Lee, Celine Sze Ling Chui, Sang Joon Son, Rae Woong Park, Seng Chan You   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Mortality and cardiovascular outcomes in randomized controlled trials comparing angiotensin receptor antagonists and ACE inhibitors versus ACE inhibitors alone in patients with heart failure.

, 2013
Mortality and cardiovascular outcomes in randomized controlled trials comparing angiotensin receptor antagonists and ACE inhibitors versus ACE inhibitors alone in patients with heart failure.
Inder Anand (365855), Gregory Arutiunov (365856), Andrea Kuenzli (365854), Rizwan Afzal (365859), Leo C. Kum (365857), Robert McKelvie (365858), Heiner C. Bucher (134728), Michel White (303419), Alain J. Nordmann (365860)   +8 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

SGLT2 Inhibitors: Statins or ACE-Inhibitors of the 21st Century? [PDF]

J Clin Med, 2023
Correale M, Tricarico L, Iacoviello M, Brunetti ND.   +3 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

[ACE inhibitors and their clinical significance]

, 1987
With the availability of orally active angiotensin converting enzyme (ACE) inhibitors, it has become possible to chronically inhibit the renin-angiotensin system.
Nussberger, J., Brunner, H. R., Waeber, B.   +2 more
core  

Angiotensin converting enzyme (ACE) inhibitors and cough [PDF]

, 1992
Individuals taking ACE inhibitors are at increased risk of developing a dry, nonproductive cough. The frequency of cough has been reported from as low as 0.5% to as high as 37%.
Evans, Barbara L
core