Results 101 to 110 of about 11,854 (255)

ACE Inhibitory Peptides Derived from Muscovy Duck (Cairina moschata) Plasma. [PDF]

Foods, 2022
Zhu Z, Guo H, Xu Y, Pius Bassey A, Ali A, Huang M, Huang J.   +6 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Screening and Molecular Mechanisms of Novel ACE-Inhibitory Peptides from Gracilariopsis lemaneiformis. [PDF]

Int J Mol Sci, 2022
Su Y, Chen S, Shen J, Yi Z, Liu S, Cai S, Pan N, Qiao K, Chen X, Chen B, Xu M, Yang S, Liu Z.   +12 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on HUVECs

Frontiers in Nutrition
IntroductionHypertension is a chronic cardiovascular disease, which can trigger some disease such as heart failure, loss of vision or kidney. There were various peptides derived from food that are recognized for their ability to inhibit ACE activity ...
Huan Xiang, Huan Xiang, Huan Xiang, Hui Huang, Hui Huang, Hui Huang, Yanqiu Shao, Shuxian Hao, Shuxian Hao, Shuxian Hao, Laihao Li, Laihao Li, Laihao Li, Ya Wei, Ya Wei, Ya Wei, Shengjun Chen, Shengjun Chen, Shengjun Chen, Yongqiang Zhao, Yongqiang Zhao, Yongqiang Zhao   +21 more
doaj   +1 more source

Isolation, virtual screening, action mechanisms, chelation with zinc ions, and stability of ACE-inhibitory peptides from ginkgo seed globulin. [PDF]

RSC Adv, 2023
Gao W, Liu M, Wang Y.
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

In Silico Screening of Bioactive Peptides in Stout Beer and Analysis of ACE Inhibitory Activity

Foods
Stout beer was selected as the research object to screen angiotensin-converting enzyme (ACE) inhibitory peptides. The peptide sequences of stout beer were identified using ultra-performance liquid chromatography-quadrupole-Orbitrap mass spectrometry with de novo, and 41 peptides were identified with high confidence. Peptide Ranker was used to score the
Tian, Wenhui, Zhang, Cui, Zheng, Qi, Hu, Shumin, Yan, Weiqiang, Yue, Ling, Chen, Zhijun, Zhang, Ci, Kong, Qiulian, Sun, Liping   +9 more
openaire   +3 more sources

Identification of novel α-glucosidase and ACE inhibitory peptides from Douchi using peptidomics approach and molecular docking. [PDF]

Food Chem X, 2023
Guo W, Xiao Y, Fu X, Long Z, Wu Y, Lin Q, Ren K, Jiang L.   +7 more
europepmc   +1 more source