Results 201 to 210 of about 82,991 (273)

Contemporary Guideline-Directed Medical Therapy for Heart Failure in the United States: The EMPACE Study. [PDF]

J Am Heart Assoc
Greene SJ, Adam A, Schmedt N, Carlsen C, Brand M, Davies E, Jouaville Abrouk LS, Prochaska JH, Tran P, Alhamdow A.   +9 more
europepmc   +1 more source

Comparative effectiveness of pharmacotherapy for heart failure with preserved ejection fraction: A systematic review and network meta‐analysis

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3137-3145, April 2026.
Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting adiposity is central to HFpEF pathogenesis. We conducted an updated network meta‐analysis to compare the efficacy of emerging and established HFpEF therapies ...
Szu‐Han Chen, Yu‐Wen Tseng, Chi‐Jung Huang, Shu‐Mei Yang, Marat Fudim, Shao‐Yuan Chuang, Shih‐Hsien Sung, Hao‐Min Cheng   +7 more
wiley   +1 more source

Cardiovascular medications and treatment outcomes in multiple myeloma: insights from phase III clinical trials. [PDF]

Sci Rep
Abuhelwa AY, Almansour SA, Al-Shamsi HO, Abuhelwa Z, Alqudah MAY, Bustanji Y, Semreen MH, Alzoubi KH, Modi ND, McKinnon RA, Sorich MJ, Hopkins AM.   +11 more
europepmc   +1 more source

Added Value of Rotational Mechanics to Longitudinal Indices in the Risk Stratification of Patients With Left Ventricular Hypertrophy

Echocardiography, Volume 43, Issue 4, April 2026.
The present study shows how 2D‐speckle tracking echocardiographic measures of myocardial rotational mechanics provide valuable information about the LVEF spectrum in patients with left ventricular hypertrophy. The primary outcome of interest is that rotational gradient (RG) is closely linked to global longitudinal strain (GLS).
Juan Geraldo, Celia Gil, Alejandro Queipo, Guillermo García‐Martín, Ester Galiana, Alberto Hidalgo, Paula Gramage, Hector Martinez‐Navarro, Jorge Lowenstein, Ildefonso Roldán, Vicente Mora   +10 more
wiley   +1 more source

Age‐Stratified Performance of the TAPSE/sPAP Ratio as a Marker of Right Ventricular‐Pulmonary Arterial Coupling in Chronic Kidney Disease

Echocardiography, Volume 43, Issue 4, April 2026.
The echocardiographic TAPSE/sPAP ratio independently predicts advanced CKD stage (adjusted OR 2.08 per 0.10‐unit decrease; bootstrap AUC 0.735). Performance is excellent in patients younger than 65 years (AUC 0.819, sensitivity 78.6%, and specificity 86.8%) but attenuated in older adults (AUC 0.579), supporting age‐stratified thresholds for cardiorenal
Görkem Yıldız, Tolga Kunak
wiley   +1 more source

An Uncommon Case of Bowel Angioedema Due to Lisinopril. [PDF]

Cureus
Vidal Carrion C, Warshaw H, Uppalapati S, Ahmed Z, Desai M.   +4 more
europepmc   +1 more source

Patient Characteristics and Clinical Outcomes in a Specialist Hypertension Clinic: A Pragmatic Real‐World Single‐Center Observational Study

The Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Patients referred to specialist hypertension clinics often have complex disease characterized by secondary causes, treatment resistance and coexisting kidney disease. Real‐world outcome data in this setting remain limited. We conducted a retrospective cohort study of 199 patients attending a tertiary hypertension clinic between January 2017 ...
William R. Marshall, Henry H. L. Wu, Sharmilee Rengarajan, David I. New, Dimitrios Poulikakos, Rajkumar Chinnadurai   +5 more
wiley   +1 more source

Delayed Onset Unilateral Tongue Edema From ACE Inhibitor-Induced Angioedema. [PDF]

Clin Case Rep
Seki M, Minami S, Kobayashi T, Young C, Yoshida A.   +4 more
europepmc   +1 more source

Beyond blood pressure: the renin-angiotensin system as an innovative driver and therapeutic target in pathological scarring. [PDF]

Front Pharmacol
Shi BH, Zhang XG, Fang QQ, Xu K, Chen XL, Tan WQ, Wang SJ.   +6 more
europepmc   +1 more source

Associations of Neprilysin and Its Coding Gene Variation With Hypertension in Chinese Adults

The Journal of Clinical Hypertension, Volume 28, Issue 4, April 2026.
ABSTRACT Neprilysin (NEP) degrades several vasoactive peptides and may contribute to blood pressure maintenance. This study aims to examine the associations between serum NEP levels and variants at its coding gene and hypertension in a general Chinese population.
Junting Hu, Jing Duan, Jiexiang Jing, Qiu Zhang, Xianfeng Yu, Rongyan Zhang, Yuting Jia, Mingzhe Du, Penghao Wang, Xueyang Zhang, Yibing Jin, Xiangdong Yang, Mingzhi Zhang, Hao Peng, Yun Shen   +14 more
wiley   +1 more source